PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16870618-7	2006	We have also shown that cAMP inhibits Ca(2+)-induced nuclear export of the MEF2 co-repressor HDAC5 and prevents Ca(2+)-stimulated nuclear import of the MEF2 co-activator NFAT3/c4.	Cyclic AMP	24-28	histone deacetylase 5	Homo sapiens	93-98	
16870618-8	2006	Our results suggest that cAMP interferes with MEF2D-mediated gene expression at multiple levels by antagonizing the derepression of MEF2D by HDAC5 and by inhibiting recruitment of the co-activator NFAT.	Cyclic AMP	25-29	histone deacetylase 5	Homo sapiens	141-146	
33000885-7	2020	Second, cAMP-induced iNOS expression and PP2Ac nitration were decreased by treatment with TSA, an inhibitor of histone deacetylase 5 (HDAC5).	Cyclic AMP	8-12	histone deacetylase 5	Homo sapiens	111-132	
33000885-7	2020	Second, cAMP-induced iNOS expression and PP2Ac nitration were decreased by treatment with TSA, an inhibitor of histone deacetylase 5 (HDAC5).	Cyclic AMP	8-12	histone deacetylase 5	Homo sapiens	134-139	
28635037-6	2018	In this study, we report that cocaine and cAMP signaling in striatum produced differential phosphorylation and subcellular localization of HDAC4 and HDAC5.	Cyclic AMP	42-46	histone deacetylase 5	Homo sapiens	149-154	
33000885-8	2020	cAMP-induced phosphorylation of CaMKII and HDAC5 was suppressed by treatment with U73122 (an inhibitor of phospholipase C) or transfection of PLCepsilon siRNA.	Cyclic AMP	0-4	histone deacetylase 5	Homo sapiens	43-48	
29508277-0	2018	BMAL1 functions as a cAMP-responsive coactivator of HDAC5 to regulate hepatic gluconeogenesis.	Cyclic AMP	21-25	histone deacetylase 5	Homo sapiens	52-57	
22243740-3	2012	(2012) describe a cAMP-dependent signaling pathway that regulates nuclear accumulation of HDAC5, suggesting a mechanism to couple cocaine with changes in HDAC5 function.	Cyclic AMP	18-22	histone deacetylase 5	Homo sapiens	90-95	
27900262-8	2016	The decrease of both Hdac5 and Hdac6 by hypoxia was associated with altered expression of adipokines and of the inducible cAMP early repressor (Icer), a key repressor that is defective in human and mice obesity.	Cyclic AMP	122-126	histone deacetylase 5	Homo sapiens	21-26	
23297420-2	2013	cAMP signaling stimulates nuclear import of HDAC4 and HDAC5, but the underlying mechanisms remain to be elucidated.	Cyclic AMP	0-4	histone deacetylase 5	Homo sapiens	54-59	
22243740-3	2012	(2012) describe a cAMP-dependent signaling pathway that regulates nuclear accumulation of HDAC5, suggesting a mechanism to couple cocaine with changes in HDAC5 function.	Cyclic AMP	18-22	histone deacetylase 5	Homo sapiens	154-159	
22243750-0	2012	Histone deacetylase 5 limits cocaine reward through cAMP-induced nuclear import.	Cyclic AMP	52-56	histone deacetylase 5	Homo sapiens	0-21	
22243750-2	2012	We report here that cocaine and cyclic adenosine monophosphate (cAMP) signaling induce the transient nuclear accumulation of HDAC5 in rodent striatum.	Cyclic AMP	32-62	histone deacetylase 5	Homo sapiens	125-130	
22243750-2	2012	We report here that cocaine and cyclic adenosine monophosphate (cAMP) signaling induce the transient nuclear accumulation of HDAC5 in rodent striatum.	Cyclic AMP	64-68	histone deacetylase 5	Homo sapiens	125-130	
22243750-3	2012	We show that cAMP-stimulated nuclear import of HDAC5 requires a signaling mechanism that involves transient, protein phosphatase 2A (PP2A)-dependent dephosphorylation of a Cdk5 site (S279) found within the HDAC5 nuclear localization sequence.	Cyclic AMP	13-17	histone deacetylase 5	Homo sapiens	47-52	
22243750-3	2012	We show that cAMP-stimulated nuclear import of HDAC5 requires a signaling mechanism that involves transient, protein phosphatase 2A (PP2A)-dependent dephosphorylation of a Cdk5 site (S279) found within the HDAC5 nuclear localization sequence.	Cyclic AMP	13-17	histone deacetylase 5	Homo sapiens	206-211	
20716686-4	2010	Here we show that cAMP-activated protein kinase A (PKA) specifically phosphorylates HDAC5 and prevents its export from the nucleus, leading to suppression of gene transcription.	Cyclic AMP	18-22	histone deacetylase 5	Homo sapiens	84-89	
20716686-9	2010	Our findings identify HDAC5 as a substrate of PKA and reveal a cAMP/PKA-dependent pathway that controls HDAC5 nucleocytoplasmic shuttling and represses gene transcription.	Cyclic AMP	63-67	histone deacetylase 5	Homo sapiens	22-27	
20716686-9	2010	Our findings identify HDAC5 as a substrate of PKA and reveal a cAMP/PKA-dependent pathway that controls HDAC5 nucleocytoplasmic shuttling and represses gene transcription.	Cyclic AMP	63-67	histone deacetylase 5	Homo sapiens	104-109