PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7738162-6	1995	Hepatocytes were placed in culture and the actions of insulin, glucagon and cAMP on glucokinase and phosphoenolpyruvate carboxykinase mRNAs were studied.	Cyclic AMP	76-80	glucokinase	Homo sapiens	84-95	
1618925-6	1992	In liver, glucokinase gene expression is regulated by insulin and cAMP, whereas in the beta cell it is regulated by glucose.	Cyclic AMP	66-70	glucokinase	Homo sapiens	10-21	
3032541-7	1987	Tyrosine amino-transferase, serine dehydratase, tryptophan oxygenase, and glucokinase are also regulated by cAMP, in part at the level of specific messenger RNA synthesis.	Cyclic AMP	108-112	glucokinase	Homo sapiens	74-85	
2185104-3	1990	Expression of this enzyme is differentially regulated; hepatic glucokinase is stimulated by insulin and repressed by cAMP, whereas beta-cell glucokinase activity is increased by glucose.	Cyclic AMP	117-121	glucokinase	Homo sapiens	63-74	
2852023-4	1988	Regulation of cAMP levels by glucagon, insulin, and catecholamines accounts in large part for minute-to-minute hormonal control of pathway flux in fed animals and during the transition from fed to starved; second, cAMP plays a key role in regulation of gene transcription of phosphoenolpyruvate carboxykinase, pyruvate kinase, glucokinase, and probably 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.	Cyclic AMP	14-18	glucokinase	Homo sapiens	327-338	
2852023-4	1988	Regulation of cAMP levels by glucagon, insulin, and catecholamines accounts in large part for minute-to-minute hormonal control of pathway flux in fed animals and during the transition from fed to starved; second, cAMP plays a key role in regulation of gene transcription of phosphoenolpyruvate carboxykinase, pyruvate kinase, glucokinase, and probably 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.	Cyclic AMP	214-218	glucokinase	Homo sapiens	327-338	
2852023-5	1988	Cyclic AMP acts to induce synthesis of mRNA for phosphoenolpyruvate carboxykinase and probably fructose 1, 6-bisphosphatase while it suppresses transcription of the genes for pyruvate kinase and glucokinase.	Cyclic AMP	0-10	glucokinase	Homo sapiens	195-206