PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10430097-0	1999	Synergistic effects of retinoic acid and 8-chloro-adenosine 3",5"-cyclic monophosphate on the regulation of retinoic acid receptor beta and apoptosis: involvement of mitochondria.	8-chloro-cyclic adenosine monophosphate	41-86	retinoic acid receptor beta	Homo sapiens	108-135	
10718618-0	2000	Synergistic effects of 8-Cl-cAMP and retinoic acids in the inhibition of growth and induction of apoptosis in ovarian cancer cells: induction of retinoic acid receptor beta.	8-chloro-cyclic adenosine monophosphate	23-32	retinoic acid receptor beta	Homo sapiens	145-172	
10718618-6	2000	8-Cl-cAMP acted synergistically with RA in inducing and activating retinoic acid receptor beta (RARbeta) which correlates with growth inhibition and apoptosis in both cell types.	8-chloro-cyclic adenosine monophosphate	0-9	retinoic acid receptor beta	Homo sapiens	67-94	
10718618-6	2000	8-Cl-cAMP acted synergistically with RA in inducing and activating retinoic acid receptor beta (RARbeta) which correlates with growth inhibition and apoptosis in both cell types.	8-chloro-cyclic adenosine monophosphate	0-9	retinoic acid receptor beta	Homo sapiens	96-103	
10718618-8	2000	Furthermore, mutations in CRE-related motif within the RARbeta promoter resulted in loss of both transcriptional activation of RARbeta and synergy between RA and 8-Cl-cAMP.	8-chloro-cyclic adenosine monophosphate	162-171	retinoic acid receptor beta	Homo sapiens	55-62	
10718618-12	2000	Thus, combined treatment with RA and 8-Cl-cAMP may provide an effective means for inducing RARbeta expression leading to apoptosis in ovarian cancer cells.	8-chloro-cyclic adenosine monophosphate	37-46	retinoic acid receptor beta	Homo sapiens	91-98	
10208436-2	1999	The cyclic AMP analog, 8-Cl-cAMP, acted synergistically with RA in inducing and activating retinoic acid receptor beta (RARbeta) which correlated with the growth inhibition, cell cycle arrest, and apoptosis in both cell types.	8-chloro-cyclic adenosine monophosphate	23-32	retinoic acid receptor beta	Homo sapiens	91-118	
10208436-2	1999	The cyclic AMP analog, 8-Cl-cAMP, acted synergistically with RA in inducing and activating retinoic acid receptor beta (RARbeta) which correlated with the growth inhibition, cell cycle arrest, and apoptosis in both cell types.	8-chloro-cyclic adenosine monophosphate	23-32	retinoic acid receptor beta	Homo sapiens	120-127	
10208436-5	1999	Furthermore, mutations in a CRE-related motif within the RARbeta promoter resulted in loss of both transcriptional activation of RARbeta and synergy between RA and 8-Cl-cAMP.	8-chloro-cyclic adenosine monophosphate	164-173	retinoic acid receptor beta	Homo sapiens	57-64