PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8352540-0	1993	C-myc expression is down-regulated in mafosfamide-treated HL-60 cells undergoing apoptosis.	mafosfamide	38-49	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	0-5	
8352540-2	1993	Since we have previously shown apoptosis to occur in HL-60 leukemic cells exposed to the prodrug Mafosfamide (ASTA Z 7557), the present study was undertaken to examine the levels of c-myc mRNA transcripts in such cells.	mafosfamide	97-108	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	182-187	
8352540-5	1993	After 6 and 24 hours of Mafosfamide-exposure, however, there was a dose- and time-dependent decrease in c-myc transcripts.	mafosfamide	24-35	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	104-109	
8352540-7	1993	Morphological, biochemical and ultrastructural evidence of apoptosis accompanied the Mafosfamide-induced c-myc mRNA down-regulation at 24 hours.	mafosfamide	85-96	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	105-110	
8352540-8	1993	We conclude that, in the context of Mafosfamide-treated HL-60 cells, upregulation of c-myc mRNA transcription was not fundamental for the activation of the apoptotic cascade.	mafosfamide	36-47	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	85-90