PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17192628-3	2006	Furthermore, it seems that activation of alpha7 nAChR is the mechanism by which galantamine protects against thapsigargin and beta-amyloid-induced cell death (Arias et al., 2004), as well as in neuroprotection exerted by NIC against tumor necrosis factor alpha (Gahring et al., 2003).	Galantamine	80-91	tumor necrosis factor	Mus musculus	233-260	
18639629-5	2009	Peripheral administration of the acetylcholinesterase inhibitor galantamine significantly reduced serum TNF levels through vagus nerve signaling, and protected against lethality during murine endotoxemia.	Galantamine	64-75	tumor necrosis factor	Mus musculus	104-107	
18639629-6	2009	Administration of a centrally-acting muscarinic receptor antagonist abolished the suppression of TNF by galantamine, indicating that suppressing acetylcholinesterase activity, coupled with central muscarinic receptors, controls peripheral cytokine responses.	Galantamine	104-115	tumor necrosis factor	Mus musculus	97-100	
30586550-6	2019	Interestingly, daily intraperitoneal administration of galantamine, an inhibitor of acetylcholinesterase, reversed cognitive dysfunction in surgery mice and attenuated accumulation of microglia and protein levels of IL-1beta, IL-6 and TNF-alpha in the hippocampus.	Galantamine	55-66	tumor necrosis factor	Mus musculus	235-244	
31024522-4	2019	Forebrain-selective genetic ablation of acetylcholine release and vagotomy abolished the suppression of serum TNF by the centrally-acting cholinergic drug galantamine in murine endotoxemia.	Galantamine	155-166	tumor necrosis factor	Mus musculus	110-113	
26521029-7	2015	Galantamine reduced the total area of amyloid load within the hippocampus of transgenic APP/PS1 mice, inhibited astrocyte activation as assessed by immunohistochemistry and decreased intracellular TNF-alpha and IL-6 expression as determined by immunofluorescence.	Galantamine	0-11	tumor necrosis factor	Mus musculus	197-206	
29669582-10	2018	Galantamine decreased the expression of microglia and astrocyte markers (CD11b and GFAP), pro-inflammatory cytokines (IL-1beta, IL-6, and TNF-alpha), and NF-kappaB p65 in the hippocampus of LPS-exposed mice.	Galantamine	0-11	tumor necrosis factor	Mus musculus	138-147