PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31489998-0 2020 Guanylate-binding protein-2 inhibits colorectal cancer cell growth and increases the sensitivity to paclitaxel of paclitaxel-resistant colorectal cancer cells by interfering Wnt signaling. Paclitaxel 100-110 guanylate binding protein 2 Homo sapiens 0-27 31489998-0 2020 Guanylate-binding protein-2 inhibits colorectal cancer cell growth and increases the sensitivity to paclitaxel of paclitaxel-resistant colorectal cancer cells by interfering Wnt signaling. Paclitaxel 114-124 guanylate binding protein 2 Homo sapiens 0-27 31489998-4 2020 In this study, the authors are determined to dig into the role that GBP-2 plays in the sensitivity of CRC to PTX, therefore, possibly indicating a promising gene therapy target for CRC. Paclitaxel 109-112 guanylate binding protein 2 Homo sapiens 68-73 31489998-8 2020 The level of GBP-2 mRNA and protein in PTX-resistant CRC cell lines was significantly lower than in nonresistant cell lines. Paclitaxel 39-42 guanylate binding protein 2 Homo sapiens 13-18 31489998-9 2020 Forced exogenous expression of GBP-2 in PTX-resistant CRC cell lines resulted in more sensitivity to PTX because of the demonstration of less cell proliferation, invasion, and more apoptosis. Paclitaxel 40-43 guanylate binding protein 2 Homo sapiens 31-36 31489998-9 2020 Forced exogenous expression of GBP-2 in PTX-resistant CRC cell lines resulted in more sensitivity to PTX because of the demonstration of less cell proliferation, invasion, and more apoptosis. Paclitaxel 101-104 guanylate binding protein 2 Homo sapiens 31-36 31489998-11 2020 GBP-2 upregulation could enhance the killing effect of PTX in both PTX-sensitive CRC cells and PTX-resistant CRC cells by suppressing Wnt signaling. Paclitaxel 55-58 guanylate binding protein 2 Homo sapiens 0-5 31489998-11 2020 GBP-2 upregulation could enhance the killing effect of PTX in both PTX-sensitive CRC cells and PTX-resistant CRC cells by suppressing Wnt signaling. Paclitaxel 67-70 guanylate binding protein 2 Homo sapiens 0-5 31489998-11 2020 GBP-2 upregulation could enhance the killing effect of PTX in both PTX-sensitive CRC cells and PTX-resistant CRC cells by suppressing Wnt signaling. Paclitaxel 67-70 guanylate binding protein 2 Homo sapiens 0-5 34294680-7 2021 Moreover, paclitaxel upregulates GBP2 expression, and paclitaxel-induced apoptotic activity was distinctively compromised by knockout of GBP2 in CML cells. Paclitaxel 10-20 guanylate binding protein 2 Homo sapiens 33-37 34294680-7 2021 Moreover, paclitaxel upregulates GBP2 expression, and paclitaxel-induced apoptotic activity was distinctively compromised by knockout of GBP2 in CML cells. Paclitaxel 10-20 guanylate binding protein 2 Homo sapiens 137-141 34294680-7 2021 Moreover, paclitaxel upregulates GBP2 expression, and paclitaxel-induced apoptotic activity was distinctively compromised by knockout of GBP2 in CML cells. Paclitaxel 54-64 guanylate binding protein 2 Homo sapiens 137-141