PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23108393-5	2013	We report that Sgk1-dependent regulation of RANBP1 has functional consequences on both mitotic microtubule activity and taxol sensitivity of cancer cells.	Paclitaxel	120-125	RAN binding protein 1	Homo sapiens	44-50	
31163384-5	2019	Specifically, SGK1 affects paclitaxel sensitivity in RKO colon carcinoma cells by modulating the specificity protein 1 (SP1)-dependent expression of Ran-specific GTPase-activating protein (RANBP1), a member of the GTP-binding nuclear protein Ran (RAN) network that is required for the organization and function of the mitotic spindle.	Paclitaxel	27-37	RAN binding protein 1	Homo sapiens	189-195	
34974521-0	2022	CD147 supports paclitaxel resistance via interacting with RanBP1.	Paclitaxel	15-25	RAN binding protein 1	Homo sapiens	58-64	
34974521-13	2022	Furthermore, we showed that RanBP1 mediated CD147-regulated microtubule stability and dynamics as well as response to paclitaxel treatment.	Paclitaxel	118-128	RAN binding protein 1	Homo sapiens	28-34	
34974521-14	2022	These results demonstrated that CD147 regulated paclitaxel response by interacting with the C-terminal tail of RanBP1 and targeting CD147 may be a promising strategy for preventing paclitaxel resistant.	Paclitaxel	48-58	RAN binding protein 1	Homo sapiens	111-117	
34974521-14	2022	These results demonstrated that CD147 regulated paclitaxel response by interacting with the C-terminal tail of RanBP1 and targeting CD147 may be a promising strategy for preventing paclitaxel resistant.	Paclitaxel	181-191	RAN binding protein 1	Homo sapiens	111-117	
29340013-4	2017	Our previous work showed that the effectiveness of the spindle poison paclitaxel in inhibiting cancer cell growth was dependent on the expression of RANBP1, a regulatory target of the serine/threonine kinase SGK1.	Paclitaxel	70-80	RAN binding protein 1	Homo sapiens	149-155	
19270727-0	2009	RanBP1 downregulation sensitizes cancer cells to taxol in a caspase-3-dependent manner.	Paclitaxel	49-54	RAN binding protein 1	Homo sapiens	0-6	
19270727-4	2009	Several observations indicate that RanBP1 contributes to regulate the function of the mitotic apparatus: RanBP1 inactivation yields hyperstable MTs and induces apoptosis during mitosis, reminiscent of the effects of the MT-stabilizing drug taxol.	Paclitaxel	240-245	RAN binding protein 1	Homo sapiens	35-41	
19270727-5	2009	Here we have investigated the influence of RanBP1 on spontaneous and taxol-induced apoptosis in transformed cells.	Paclitaxel	69-74	RAN binding protein 1	Homo sapiens	43-49	
19270727-7	2009	Furthermore, RanBP1-interfered cells show an increased apoptotic response to taxol compared to their counterpart with normal or high RanBP1 levels, and this response is caspase-3 dependent.	Paclitaxel	77-82	RAN binding protein 1	Homo sapiens	13-19	
19270727-7	2009	Furthermore, RanBP1-interfered cells show an increased apoptotic response to taxol compared to their counterpart with normal or high RanBP1 levels, and this response is caspase-3 dependent.	Paclitaxel	77-82	RAN binding protein 1	Homo sapiens	133-139