PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30578561-11	2019	Knockout of IL-1 receptors prevented the development of acute pain induced by paclitaxel in mice.	Paclitaxel	78-88	interleukin 1 complex	Mus musculus	12-16	
1350792-5	1992	But Taxol seemed to be a weak inducer of the two interleukins IL-1 and IL-2, since their detection occurred late in the cell culture supernatants.	Paclitaxel	4-9	interleukin 1 complex	Mus musculus	62-66	
25887886-4	2015	Tumors from mice treated with combined therapy of paclitaxel and the IL1 receptor antagonist anakinra exhibit increased number of M2 macrophages and vessel leakiness when compared with paclitaxel monotherapy-treated mice, indicating a prometastatic role of M2 macrophages in the IL1beta-deprived microenvironment.	Paclitaxel	185-195	interleukin 1 complex	Mus musculus	69-72	
9317152-1	1997	Activation of macrophages by LPS and taxol results in production of IL-1, IL-6, TNF-alpha, and granulocyte-macrophage CSF (GM-CSF), which are involved in regulating hemopoiesis, inflammation, and immune responses.	Paclitaxel	37-42	interleukin 1 complex	Mus musculus	68-72	
1353517-7	1992	Induction of TNF mRNA by 10 microM taxol was detectable at 45 min of stimulation, maximal at 90 min, and evident for at least 8 h. The same low concentration of taxol also induced interleukin 1 (IL-1) alpha and beta mRNA expression.	Paclitaxel	35-40	interleukin 1 complex	Mus musculus	180-193	
1353517-7	1992	Induction of TNF mRNA by 10 microM taxol was detectable at 45 min of stimulation, maximal at 90 min, and evident for at least 8 h. The same low concentration of taxol also induced interleukin 1 (IL-1) alpha and beta mRNA expression.	Paclitaxel	161-166	interleukin 1 complex	Mus musculus	180-193	
1353517-8	1992	We conclude that taxol triggers macrophages for TNF and IL-1 production.	Paclitaxel	17-22	interleukin 1 complex	Mus musculus	56-60