PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9317152-1 1997 Activation of macrophages by LPS and taxol results in production of IL-1, IL-6, TNF-alpha, and granulocyte-macrophage CSF (GM-CSF), which are involved in regulating hemopoiesis, inflammation, and immune responses. Paclitaxel 37-42 interleukin 1 complex Mus musculus 68-72 1350792-5 1992 But Taxol seemed to be a weak inducer of the two interleukins IL-1 and IL-2, since their detection occurred late in the cell culture supernatants. Paclitaxel 4-9 interleukin 1 complex Mus musculus 62-66 1353517-7 1992 Induction of TNF mRNA by 10 microM taxol was detectable at 45 min of stimulation, maximal at 90 min, and evident for at least 8 h. The same low concentration of taxol also induced interleukin 1 (IL-1) alpha and beta mRNA expression. Paclitaxel 35-40 interleukin 1 complex Mus musculus 180-193 1353517-7 1992 Induction of TNF mRNA by 10 microM taxol was detectable at 45 min of stimulation, maximal at 90 min, and evident for at least 8 h. The same low concentration of taxol also induced interleukin 1 (IL-1) alpha and beta mRNA expression. Paclitaxel 161-166 interleukin 1 complex Mus musculus 180-193 1353517-8 1992 We conclude that taxol triggers macrophages for TNF and IL-1 production. Paclitaxel 17-22 interleukin 1 complex Mus musculus 56-60 30578561-11 2019 Knockout of IL-1 receptors prevented the development of acute pain induced by paclitaxel in mice. Paclitaxel 78-88 interleukin 1 complex Mus musculus 12-16 25887886-4 2015 Tumors from mice treated with combined therapy of paclitaxel and the IL1 receptor antagonist anakinra exhibit increased number of M2 macrophages and vessel leakiness when compared with paclitaxel monotherapy-treated mice, indicating a prometastatic role of M2 macrophages in the IL1beta-deprived microenvironment. Paclitaxel 185-195 interleukin 1 complex Mus musculus 69-72