PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33146163-1 2020 Using a combination of a synthetic substrate analogue and product standard, MmfL, a homologue of the gamma-butyrolactone biosynthetic enzyme AfsA, was shown to catalyse the condensation of dihydroxyacetone phosphate with a beta-ketoacyl thioester to form a phosphorylated butenolide intermediate in the biosynthesis of the methylenomycin furans, which induce methlenomycin antibiotic production in Streptomyces coelicolor A3(2). methylenomycin A 323-337 mmfL Streptomyces coelicolor A3(2) 76-80