PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18984863-5 2009 Whereas young PSF1(+/-) mutant mice develop normally, are fertile, and have no obvious differences in hematopoiesis in the steady state compared with wild-type mice, intravenous injection of 5-fluorouracil (5-FU) is lethal in PSF1(+/-) mice, resulting from a delay in induction of HSC proliferation during ablated BM reconstitution. Fluorouracil 191-205 GINS complex subunit 1 (Psf1 homolog) Mus musculus 226-230 24244394-5 2013 We have previously reported that haploinsufficiency of PSF1 resulted in failure of acute proliferation of bone marrow hematopoietic stem cells (HSCs) during reconstitution of bone marrow ablated by 5-FU treatment. Fluorouracil 198-202 GINS complex subunit 1 (Psf1 homolog) Mus musculus 55-59