PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9796980-0 1998 Effect of the combined treatment with 5-fluorouracil, gamma-interferon or folinic acid on carcinoembryonic antigen expression in colon cancer cells. Fluorouracil 38-52 CEA cell adhesion molecule 3 Homo sapiens 90-114 11091713-9 1999 CONCLUSION: A false-positive increase in CEA, NCC-ST-439 or BCA225 might be caused by treatment with oral 5-FU or its derivatives. Fluorouracil 106-110 CEA cell adhesion molecule 3 Homo sapiens 41-44 9796980-1 1998 5-Fluorouracil (5-FU) and human recombinant gamma-interferon (gamma-IFN) were found to increase the expression of carcinoembryonic antigen (CEA) in human cancer cells in vitro. Fluorouracil 0-14 CEA cell adhesion molecule 3 Homo sapiens 114-138 9796980-1 1998 5-Fluorouracil (5-FU) and human recombinant gamma-interferon (gamma-IFN) were found to increase the expression of carcinoembryonic antigen (CEA) in human cancer cells in vitro. Fluorouracil 0-14 CEA cell adhesion molecule 3 Homo sapiens 140-143 9796980-1 1998 5-Fluorouracil (5-FU) and human recombinant gamma-interferon (gamma-IFN) were found to increase the expression of carcinoembryonic antigen (CEA) in human cancer cells in vitro. Fluorouracil 16-20 CEA cell adhesion molecule 3 Homo sapiens 114-138 9796980-1 1998 5-Fluorouracil (5-FU) and human recombinant gamma-interferon (gamma-IFN) were found to increase the expression of carcinoembryonic antigen (CEA) in human cancer cells in vitro. Fluorouracil 16-20 CEA cell adhesion molecule 3 Homo sapiens 140-143 9796980-3 1998 Treatment of two human colon cancer cell lines (HT-29 and WiDr) with 5-FU + gamma-IFN resulted in an increase of CEA expression higher than that obtainable with both agents alone, although no synergistic effects were obtained. Fluorouracil 69-73 CEA cell adhesion molecule 3 Homo sapiens 113-116 21541578-1 1996 We investigated whether carcinoembryonic antigen (CEA) could be used to predict the response and survival of patients treated with 5-FU. Fluorouracil 131-135 CEA cell adhesion molecule 3 Homo sapiens 24-48 9492838-3 1998 After the operation, 5-FU alone and low doses of CDDP and 5-FU were administered, but the level of serum CEA elevated and CT scanning showed multiple liver metastases. Fluorouracil 58-62 CEA cell adhesion molecule 3 Homo sapiens 105-108 9279352-8 1997 5-FU, CDDP and Leucovorin were administered, but the CEA level became more and more elevated. Fluorouracil 0-4 CEA cell adhesion molecule 3 Homo sapiens 53-56 9020952-3 1997 After arterial infusion chemotherapy consisting of CDDP, epirubicin and 5-FU, the tumor size and serum level of CEA were significantly decreased. Fluorouracil 72-76 CEA cell adhesion molecule 3 Homo sapiens 112-115 21541578-5 1996 Patients with CEA values reduced by greater than or equal to 30% at 2 months after the start of 5-FU infusion had a significantly longer survival period than patients with a decrease of <30%. Fluorouracil 96-100 CEA cell adhesion molecule 3 Homo sapiens 14-17 21541578-1 1996 We investigated whether carcinoembryonic antigen (CEA) could be used to predict the response and survival of patients treated with 5-FU. Fluorouracil 131-135 CEA cell adhesion molecule 3 Homo sapiens 50-53 7794002-5 1995 With re-elevated serum CEA level, subsequent intrahepatic arterial infusion of CDDP and 5-FU the nodule size reduced with normalization of the serum CEA level. Fluorouracil 88-92 CEA cell adhesion molecule 3 Homo sapiens 23-26 8968385-1 1996 Previous studies showed that 5-fluorouracil (5-FU) is capable of enhancing the membrane reactivity of the human colon carcinoma cell line HT-29 with a monoclonal antibody (COL-1) directed against carcinoembryonic antigen (CEA). Fluorouracil 29-43 CEA cell adhesion molecule 3 Homo sapiens 196-220 8968385-1 1996 Previous studies showed that 5-fluorouracil (5-FU) is capable of enhancing the membrane reactivity of the human colon carcinoma cell line HT-29 with a monoclonal antibody (COL-1) directed against carcinoembryonic antigen (CEA). Fluorouracil 29-43 CEA cell adhesion molecule 3 Homo sapiens 222-225 8968385-1 1996 Previous studies showed that 5-fluorouracil (5-FU) is capable of enhancing the membrane reactivity of the human colon carcinoma cell line HT-29 with a monoclonal antibody (COL-1) directed against carcinoembryonic antigen (CEA). Fluorouracil 45-49 CEA cell adhesion molecule 3 Homo sapiens 196-220 8968385-1 1996 Previous studies showed that 5-fluorouracil (5-FU) is capable of enhancing the membrane reactivity of the human colon carcinoma cell line HT-29 with a monoclonal antibody (COL-1) directed against carcinoembryonic antigen (CEA). Fluorouracil 45-49 CEA cell adhesion molecule 3 Homo sapiens 222-225 8968385-2 1996 In the present study, we show that short-term exposure (i.e., 1 hr) of cancer cells to 5-FU mediates a marked increase of CEA expression, that is concentration-dependent and lasts up to day 5 after treatment. Fluorouracil 87-91 CEA cell adhesion molecule 3 Homo sapiens 122-125 8968385-4 1996 This is supported by the finding that the increase of the CEA expression detected by cytofluorimetric analysis is observed not only in the parental HT-29 line, but also in its C22.20 subclone, endowed with a low basal level of CEA and with chemosensitivity to 5-FU lower than that of the parental cell line. Fluorouracil 260-264 CEA cell adhesion molecule 3 Homo sapiens 58-61 8968385-6 1996 Northern blot analysis of total RNA extracted from 5-FU-treated HT-29 or C22.20 cells shows an increase in the steady-state levels of CEA and CEA-related transcripts (e.g., biliary glycoprotein). Fluorouracil 51-55 CEA cell adhesion molecule 3 Homo sapiens 142-145 8968385-7 1996 Moreover 5-FU-mediated augmentation of the CEA transcript appears to be attributable mainly to enhanced transcription rather than to increased mRNA stability. Fluorouracil 9-13 CEA cell adhesion molecule 3 Homo sapiens 43-46 8968385-8 1996 It is concluded that induction of enhanced CEA protein expression in cancer cells treated with 5-FU could be of clinical interest for the development of immunochemotherapeutic protocols based on CEA protein as the target molecule. Fluorouracil 95-99 CEA cell adhesion molecule 3 Homo sapiens 43-46 8968385-8 1996 It is concluded that induction of enhanced CEA protein expression in cancer cells treated with 5-FU could be of clinical interest for the development of immunochemotherapeutic protocols based on CEA protein as the target molecule. Fluorouracil 95-99 CEA cell adhesion molecule 3 Homo sapiens 195-198 31689796-6 2019 Among patients with carcinoembryonic antigen (CEA) levels of <5 ng/mL at 1 month after LR, significant differences were noted only in those who underwent 5-FU/LV (HR = 0.58, P = .035) and oxaliplatin-based chemotherapy (HR = 0.38, P < .001). Fluorouracil 157-161 CEA cell adhesion molecule 3 Homo sapiens 46-49 2506832-10 1989 Their pretreatment value of CEA was lower at 13.6 and 23.8 ng/ml, respectively, and these levels were decreased to 1.0 ng/ml with administration of 5-FU with ADM and 5-FU with MMC. Fluorouracil 148-152 CEA cell adhesion molecule 3 Homo sapiens 28-31 2506832-10 1989 Their pretreatment value of CEA was lower at 13.6 and 23.8 ng/ml, respectively, and these levels were decreased to 1.0 ng/ml with administration of 5-FU with ADM and 5-FU with MMC. Fluorouracil 166-170 CEA cell adhesion molecule 3 Homo sapiens 28-31 32790589-10 2020 CONCLUSION: In radically operated stage II to IV CRC patients who received adjuvant 5-FU-based chemotherapy, a postoperatively elevated CEA alone or in combination with CA19-9, YKL-40, CRP, or IL-6, or a normal CEA combined with an elevated YKL-40 or with an elevated CRP, may indicate patients at high risk of relapse. Fluorouracil 84-88 CEA cell adhesion molecule 3 Homo sapiens 136-139 23863744-5 2013 After 8 courses of adjuvant chemotherapy with modified 5-fluorouracil/Leucovorin/oxaliplatin(mFOLFOX6), carcinoembryonic antigen( CEA)decreased to a normal level, and positron emission tomography-computed tomography(PET-CT)showed no abnormal accumulation that suggested metastasis. Fluorouracil 55-69 CEA cell adhesion molecule 3 Homo sapiens 130-133 31028570-0 2019 Enhancement of chemosensitivity in 5-fluorouracil-resistant colon cancer cells with carcinoembryonic antigen-specific RNA aptamer. Fluorouracil 35-49 CEA cell adhesion molecule 3 Homo sapiens 84-108 31028570-4 2019 However, a major issue of 5-FU therapy is the occurrence of chemoresistance, and the fact that 5-FU induces CEA overexpression, which may induce the 5-FU resistance. Fluorouracil 95-99 CEA cell adhesion molecule 3 Homo sapiens 108-111 31028570-4 2019 However, a major issue of 5-FU therapy is the occurrence of chemoresistance, and the fact that 5-FU induces CEA overexpression, which may induce the 5-FU resistance. Fluorouracil 95-99 CEA cell adhesion molecule 3 Homo sapiens 108-111 31028570-6 2019 In the present study, we tested whether protecting CEA using the CEA aptamer could enhance 5-FU sensitivity in chemoresistant LS174T colon cancer cells. Fluorouracil 91-95 CEA cell adhesion molecule 3 Homo sapiens 51-54 31028570-6 2019 In the present study, we tested whether protecting CEA using the CEA aptamer could enhance 5-FU sensitivity in chemoresistant LS174T colon cancer cells. Fluorouracil 91-95 CEA cell adhesion molecule 3 Homo sapiens 65-68 31028570-7 2019 We observed that the CEA aptamer sensitized the 5-FU-resistant colon cancer cell line to 5-FU more than five-fold (IC50 ~ 5.995 muM), compared with cells treated with 5-FU alone (IC50 ~ 31.46 muM). Fluorouracil 48-52 CEA cell adhesion molecule 3 Homo sapiens 21-24 31028570-7 2019 We observed that the CEA aptamer sensitized the 5-FU-resistant colon cancer cell line to 5-FU more than five-fold (IC50 ~ 5.995 muM), compared with cells treated with 5-FU alone (IC50 ~ 31.46 muM). Fluorouracil 89-93 CEA cell adhesion molecule 3 Homo sapiens 21-24 31028570-7 2019 We observed that the CEA aptamer sensitized the 5-FU-resistant colon cancer cell line to 5-FU more than five-fold (IC50 ~ 5.995 muM), compared with cells treated with 5-FU alone (IC50 ~ 31.46 muM). Fluorouracil 89-93 CEA cell adhesion molecule 3 Homo sapiens 21-24 31028570-10 2019 In conclusion, CEA-specific aptamer improved 5-FU sensitivity in chemoresistant colon cancer cells in vitro and in vivo, and thus represents a novel 5-FU adjuvant to overcome the chemoresistance in CRC patients. Fluorouracil 45-49 CEA cell adhesion molecule 3 Homo sapiens 15-18 31028570-10 2019 In conclusion, CEA-specific aptamer improved 5-FU sensitivity in chemoresistant colon cancer cells in vitro and in vivo, and thus represents a novel 5-FU adjuvant to overcome the chemoresistance in CRC patients. Fluorouracil 149-153 CEA cell adhesion molecule 3 Homo sapiens 15-18 26831719-8 2016 Postoperative adjuvant chemotherapy was applied in 31 CEA band-positive cases with an oral 5-fluorouracil derivative HCFU (1-hexylcarbamoyl-5-fluorouracil) for 1 year, whereas chemotherapy was not administered to CEA band-negative group. Fluorouracil 91-105 CEA cell adhesion molecule 3 Homo sapiens 54-57 26831719-8 2016 Postoperative adjuvant chemotherapy was applied in 31 CEA band-positive cases with an oral 5-fluorouracil derivative HCFU (1-hexylcarbamoyl-5-fluorouracil) for 1 year, whereas chemotherapy was not administered to CEA band-negative group. Fluorouracil 91-105 CEA cell adhesion molecule 3 Homo sapiens 213-216 27478804-0 2016 Carcinoembryonic Antigen Expression and Resistance to Radiation and 5-Fluorouracil-Induced Apoptosis and Autophagy. Fluorouracil 68-82 CEA cell adhesion molecule 3 Homo sapiens 0-24 27478804-2 2016 In this study, we investigated the effect of carcinoembryonic antigen (CEA) overexpression on UV-and 5-fluorouracil (5-FU)-induced apoptosis and autophagy in colorectal cancer cells. Fluorouracil 101-115 CEA cell adhesion molecule 3 Homo sapiens 45-69 27478804-2 2016 In this study, we investigated the effect of carcinoembryonic antigen (CEA) overexpression on UV-and 5-fluorouracil (5-FU)-induced apoptosis and autophagy in colorectal cancer cells. Fluorouracil 101-115 CEA cell adhesion molecule 3 Homo sapiens 71-74 27478804-2 2016 In this study, we investigated the effect of carcinoembryonic antigen (CEA) overexpression on UV-and 5-fluorouracil (5-FU)-induced apoptosis and autophagy in colorectal cancer cells. Fluorouracil 117-121 CEA cell adhesion molecule 3 Homo sapiens 45-69 27478804-2 2016 In this study, we investigated the effect of carcinoembryonic antigen (CEA) overexpression on UV-and 5-fluorouracil (5-FU)-induced apoptosis and autophagy in colorectal cancer cells. Fluorouracil 117-121 CEA cell adhesion molecule 3 Homo sapiens 71-74 27478804-10 2016 Decreased proportions of autophagy and apoptosis were also observed in 5-FU treated SW742- and CHO-CEA transfectants. Fluorouracil 71-75 CEA cell adhesion molecule 3 Homo sapiens 99-102 26044651-6 2015 Furthermore, we showed that rAd/CEA-RPL23 synergized with classic chemotherapeutic agent 5-fluorouracil (5-FU) and enhanced its activity against LoVo cells in vivo and in vitro. Fluorouracil 89-103 CEA cell adhesion molecule 3 Homo sapiens 32-35 26044651-6 2015 Furthermore, we showed that rAd/CEA-RPL23 synergized with classic chemotherapeutic agent 5-fluorouracil (5-FU) and enhanced its activity against LoVo cells in vivo and in vitro. Fluorouracil 105-109 CEA cell adhesion molecule 3 Homo sapiens 32-35 24293105-0 2014 Carcinoembryonic antigen expression level as a predictive factor for response to 5-fluorouracil in colorectal cancer. Fluorouracil 81-95 CEA cell adhesion molecule 3 Homo sapiens 0-24 24293105-9 2014 However, 5-FU treatment resulted in the selection of sub-populations of resistant cells that displayed increased CEA expression levels by increasing drug concentration. Fluorouracil 9-13 CEA cell adhesion molecule 3 Homo sapiens 113-116 24293105-12 2014 In comparison to the 3D spheroids of parental CHO, we observed a significantly elevated 5-FU resistance in 3D culture of the CEA-expressing CHO transfectants. Fluorouracil 88-92 CEA cell adhesion molecule 3 Homo sapiens 125-128 24293105-13 2014 Our findings suggest that the CEA level may be a suitable biomarker for predicting tumor response to 5-FU-based chemotherapy in CRC. Fluorouracil 101-105 CEA cell adhesion molecule 3 Homo sapiens 30-33 18577244-0 2008 Combined effects of 5-fluorouracil, folinic acid and oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy. Fluorouracil 20-34 CEA cell adhesion molecule 3 Homo sapiens 86-110 23267153-0 2013 CEA fluctuation during a single fluorouracil-based chemotherapy cycle for metastatic colorectal cancer. Fluorouracil 32-44 CEA cell adhesion molecule 3 Homo sapiens 0-3 17687334-0 2007 In vitro evaluation of cancer-specific NF-kappaB-CEA enhancer-promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines. Fluorouracil 82-96 CEA cell adhesion molecule 3 Homo sapiens 49-52 15967383-0 2005 Combined effects of protein kinase inhibitors and 5-fluorouracil on CEA expression in human colon cancer cells. Fluorouracil 50-64 CEA cell adhesion molecule 3 Homo sapiens 68-71 17023760-3 2006 Systemic administration of 5FU and CDDP caused her CEA level to decrease gradually and abdominal computed tomography revealed considerable reduction of the metastatic tumors and ascites. Fluorouracil 27-30 CEA cell adhesion molecule 3 Homo sapiens 51-54 15967383-1 2005 Previous studies showed that 5-fluorouracil (5-FU) and Staurosporine (ST), a protein kinase inhibitor (PKI), were able to increase the expression of carcinoembryonic antigen (CEA) in human colon cancer cells. Fluorouracil 29-43 CEA cell adhesion molecule 3 Homo sapiens 149-173 15967383-1 2005 Previous studies showed that 5-fluorouracil (5-FU) and Staurosporine (ST), a protein kinase inhibitor (PKI), were able to increase the expression of carcinoembryonic antigen (CEA) in human colon cancer cells. Fluorouracil 29-43 CEA cell adhesion molecule 3 Homo sapiens 175-178 15967383-1 2005 Previous studies showed that 5-fluorouracil (5-FU) and Staurosporine (ST), a protein kinase inhibitor (PKI), were able to increase the expression of carcinoembryonic antigen (CEA) in human colon cancer cells. Fluorouracil 45-49 CEA cell adhesion molecule 3 Homo sapiens 149-173 15967383-1 2005 Previous studies showed that 5-fluorouracil (5-FU) and Staurosporine (ST), a protein kinase inhibitor (PKI), were able to increase the expression of carcinoembryonic antigen (CEA) in human colon cancer cells. Fluorouracil 45-49 CEA cell adhesion molecule 3 Homo sapiens 175-178 15967383-6 2005 Flow cytometric analysis showed that treatment of cells with 5-FU + ST resulted in a synergistic increase of CEA expression, being higher than that obtainable with both agents alone. Fluorouracil 61-65 CEA cell adhesion molecule 3 Homo sapiens 109-112 15279063-3 2004 Patients underwent low-dose CDDP+5-FU monitoring continual CEA level. Fluorouracil 33-37 CEA cell adhesion molecule 3 Homo sapiens 59-62 12420861-5 2002 Using this approach, we demonstrated an ST-mediated increase in CEA transcript in blood specimens collected from a patient with metastatic colon cancer before receiving treatment with 5-fluorouracil/leucovorin. Fluorouracil 184-198 CEA cell adhesion molecule 3 Homo sapiens 64-67 14564514-7 2003 Combined treatment with 5-FU and CDDP gave additional effect on CEA expression in COLO201 cells. Fluorouracil 24-28 CEA cell adhesion molecule 3 Homo sapiens 64-67 12584740-0 2003 Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLA-A(*)02.01 restricted, CEA-peptide-specific cytotoxic T cells in vitro. Fluorouracil 51-65 CEA cell adhesion molecule 3 Homo sapiens 162-165 12584740-3 2003 Previous studies have shown that 5-fluorouracil (5-FU) can upregulate the expression of membrane-associated carcino-embryonic antigen (CEA), and MHC molecules in colon and breast carcinoma cell lines. Fluorouracil 33-47 CEA cell adhesion molecule 3 Homo sapiens 135-138 12584740-3 2003 Previous studies have shown that 5-fluorouracil (5-FU) can upregulate the expression of membrane-associated carcino-embryonic antigen (CEA), and MHC molecules in colon and breast carcinoma cell lines. Fluorouracil 49-53 CEA cell adhesion molecule 3 Homo sapiens 135-138 12584740-6 2003 The treatment of target cells with 5-FU, enhanced their CEA expression and susceptibility to CTL-mediated lysis. Fluorouracil 35-39 CEA cell adhesion molecule 3 Homo sapiens 56-59 12584740-7 2003 Cold competition assays confirmed these results, thus supporting the hypothesis that immune target cell lysis and 5-FU mediated enhancement were dependent on CEA peptide presentation by cancer cells. Fluorouracil 114-118 CEA cell adhesion molecule 3 Homo sapiens 158-161 12584740-9 2003 These results provide a rationale for investigating a possible new role of 5-FU as an immuno targeting amplifier agent in breast and colorectal cancer patients immunized with CEA-directed cancer vaccines. Fluorouracil 75-79 CEA cell adhesion molecule 3 Homo sapiens 175-178 12743424-3 2003 Immunoassay results show that CEA and MUC-1 expression all increase rapidly after either 5-FU or RAIT. Fluorouracil 89-93 CEA cell adhesion molecule 3 Homo sapiens 30-33 14998548-4 2004 Actually, it has been shown that the expression of CEA can be up-regulated by pharmacological agents including, antineoplastic drugs (i.e. 5-fluorouracil), cytokines (i.e. interferons or interleukin-6), differentiating agents (i.e. sodium butyrate) and protein kinase inhibitors (i.e. staurosporine). Fluorouracil 139-153 CEA cell adhesion molecule 3 Homo sapiens 51-54 12743424-2 2003 This report addressed the time-dependent dynamic alterations in the expression of three tumor-associated antigens: carcinoembryonic antigen (CEA), colon-specific antigen (CSAp) and mucin-1 (MUC-1) following chemotherapy with 5-fluorouracil (5-FU) or radioimmunotherapy (RAIT; (131)I-labeled anti-CEA IgG) in human colonic tumor xenografts. Fluorouracil 225-239 CEA cell adhesion molecule 3 Homo sapiens 115-139 12174947-3 2002 After administration of chemotherapy consisting of 5-fluorouracil (4000 mg) and epirubicin (280 mg), the pulmonary metastases disappeared and this was associated with a decrease of serum CEA levels and tumor size. Fluorouracil 51-65 CEA cell adhesion molecule 3 Homo sapiens 187-190 11277324-1 2000 Treatment with 5-fluorouracil (5-FU) or recombinant interferon-gamma (IFN), alone or in combination, was found to increase carcinoembryonic antigen (CEA) expression in several carcinoma cell lines. Fluorouracil 15-29 CEA cell adhesion molecule 3 Homo sapiens 123-147 11448920-9 2001 However, CEA significantly protected HT29 cells from undergoing apoptosis under various conditions, including confluent growth, UV light, IFN-gamma treatment, and treatment with 5-fluorouracil. Fluorouracil 178-192 CEA cell adhesion molecule 3 Homo sapiens 9-12 11300328-0 2001 CEA and CA 19-9 measurement as a monitoring parameter in metastatic colorectal cancer (CRC) under palliative first-line chemotherapy with weekly 24-hour infusion of high-dose 5-fluorouracil (5-FU) and folinic acid (FA). Fluorouracil 175-189 CEA cell adhesion molecule 3 Homo sapiens 0-15 11300328-0 2001 CEA and CA 19-9 measurement as a monitoring parameter in metastatic colorectal cancer (CRC) under palliative first-line chemotherapy with weekly 24-hour infusion of high-dose 5-fluorouracil (5-FU) and folinic acid (FA). Fluorouracil 191-195 CEA cell adhesion molecule 3 Homo sapiens 0-15 11277324-1 2000 Treatment with 5-fluorouracil (5-FU) or recombinant interferon-gamma (IFN), alone or in combination, was found to increase carcinoembryonic antigen (CEA) expression in several carcinoma cell lines. Fluorouracil 15-29 CEA cell adhesion molecule 3 Homo sapiens 149-152 11277324-1 2000 Treatment with 5-fluorouracil (5-FU) or recombinant interferon-gamma (IFN), alone or in combination, was found to increase carcinoembryonic antigen (CEA) expression in several carcinoma cell lines. Fluorouracil 31-35 CEA cell adhesion molecule 3 Homo sapiens 123-147 11277324-1 2000 Treatment with 5-fluorouracil (5-FU) or recombinant interferon-gamma (IFN), alone or in combination, was found to increase carcinoembryonic antigen (CEA) expression in several carcinoma cell lines. Fluorouracil 31-35 CEA cell adhesion molecule 3 Homo sapiens 149-152 11277324-3 2000 The results showed that exposure of cancer cells to 5-FU or to IFN resulted in increased CEA levels in terms of percentage of CEA-positive cells and mean fluorescence values, as indicated by FACS analysis. Fluorouracil 52-56 CEA cell adhesion molecule 3 Homo sapiens 89-92 11277324-3 2000 The results showed that exposure of cancer cells to 5-FU or to IFN resulted in increased CEA levels in terms of percentage of CEA-positive cells and mean fluorescence values, as indicated by FACS analysis. Fluorouracil 52-56 CEA cell adhesion molecule 3 Homo sapiens 126-129 11086424-6 2000 The total dose of 5-FU was 30.0 +/- 7.6 g in the normal CEA level group and 19.1 +/- 6.9 g in the high CEA level group. Fluorouracil 18-22 CEA cell adhesion molecule 3 Homo sapiens 56-59 11131650-0 2000 Effect of 5-fluorouracil on carcinoembryonic antigen expression and shedding at clonal level in colon cancer cells. Fluorouracil 10-24 CEA cell adhesion molecule 3 Homo sapiens 28-52 11131650-2 2000 In preclinical models CEA has been found to be up-regulated after exposure of cancer cells to 5-fluorouracil (5-FU). Fluorouracil 94-108 CEA cell adhesion molecule 3 Homo sapiens 22-25 11131650-2 2000 In preclinical models CEA has been found to be up-regulated after exposure of cancer cells to 5-fluorouracil (5-FU). Fluorouracil 110-114 CEA cell adhesion molecule 3 Homo sapiens 22-25 11131650-3 2000 In the present study, the clonal distribution of CEA and its regulation by 5-FU at clonal level was investigated using human HT-29 colon cancer cells. Fluorouracil 75-79 CEA cell adhesion molecule 3 Homo sapiens 49-52 11131650-6 2000 In all cases 5-FU was able to increase the percentage of CEA-positive cells, the amount of antigen, either in the membrane or cytosolic fractions, and the corresponding transcript. Fluorouracil 13-17 CEA cell adhesion molecule 3 Homo sapiens 57-60