PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34916479-0	2021	Galangin Enhances Anticancer Efficacy of 5-Fluorouracil in Esophageal Cancer Cells and Xenografts Through NLR Family Pyrin Domain Containing 3 (NLRP3) Downregulation.	Fluorouracil	41-55	NLR family pyrin domain containing 3	Homo sapiens	106-142	
34916479-8	2021	NLRP3 was identified as being significantly activated by 5-FU, but galangin treatment reversed the effect and inhibited NLRP3 expression, which was accompanied by downregulated interleukin-1b levels.	Fluorouracil	57-61	NLR family pyrin domain containing 3	Homo sapiens	0-5	
34916479-8	2021	NLRP3 was identified as being significantly activated by 5-FU, but galangin treatment reversed the effect and inhibited NLRP3 expression, which was accompanied by downregulated interleukin-1b levels.	Fluorouracil	57-61	NLR family pyrin domain containing 3	Homo sapiens	120-125	
35448938-6	2022	In our results, the three SCFAs could inhibit ROS expressions, NLRP3, Caspase-1, IL-1beta, IL-6, IL-18, Beclin-1 and LC3-II, when induced by 5-FU.	Fluorouracil	141-145	NLR family pyrin domain containing 3	Homo sapiens	63-68	
25389767-5	2014	Incubating the cells with 5-FU increased the expression of nucleotide-binding domain and leucine-rich repeat containing PYD-3 (NLRP3) and caspase-1.	Fluorouracil	26-30	NLR family pyrin domain containing 3	Homo sapiens	127-132	
28637493-11	2017	RESULTS: In the clinical analysis, expression and activation of NLRP3 inflammasome was clearly increased in OSCC tissues of patients who received 5-FU-based chemotherapy.	Fluorouracil	146-150	NLR family pyrin domain containing 3	Homo sapiens	64-69	
25389767-7	2014	The inhibition of the NLRP3 pathway slightly decreased the effects of 5-FU on cell viability and LDH release, suggesting that NLRP3 may be in part involved in 5-FU-induced cell death.	Fluorouracil	70-74	NLR family pyrin domain containing 3	Homo sapiens	22-27	
25389767-7	2014	The inhibition of the NLRP3 pathway slightly decreased the effects of 5-FU on cell viability and LDH release, suggesting that NLRP3 may be in part involved in 5-FU-induced cell death.	Fluorouracil	70-74	NLR family pyrin domain containing 3	Homo sapiens	126-131	
25389767-7	2014	The inhibition of the NLRP3 pathway slightly decreased the effects of 5-FU on cell viability and LDH release, suggesting that NLRP3 may be in part involved in 5-FU-induced cell death.	Fluorouracil	159-163	NLR family pyrin domain containing 3	Homo sapiens	22-27	
25389767-7	2014	The inhibition of the NLRP3 pathway slightly decreased the effects of 5-FU on cell viability and LDH release, suggesting that NLRP3 may be in part involved in 5-FU-induced cell death.	Fluorouracil	159-163	NLR family pyrin domain containing 3	Homo sapiens	126-131