PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26568264-3 2015 Here we report that three gustatory receptors, GR8a, GR66a and GR98b function together in the detection of L-canavanine, a plant-derived insecticide. Canavanine 107-119 Gustatory receptor 8a Drosophila melanogaster 47-51 22279227-7 2012 We found that L-canavanine stimulated action potentials in S-type sensilla, which were where Gr8a and Gr66a were both expressed, but not in Gr66a-expressing sensilla that did not express Gr8a. Canavanine 14-26 Gustatory receptor 8a Drosophila melanogaster 93-97 22279227-9 2012 Gr8a was narrowly required for responding to L-canavanine, in contrast to Gr66a, which was broadly required for responding to other noxious tastants. Canavanine 45-57 Gustatory receptor 8a Drosophila melanogaster 0-4 22279227-10 2012 Our data suggest that GR8a and GR66a are subunits of an L-canavanine receptor and that GR8a contributes to the specificity for L-canavanine. Canavanine 56-68 Gustatory receptor 8a Drosophila melanogaster 22-26 26568264-4 2015 Ectopic co-expression of Gr8a and Gr98b in Gr66a-expressing, bitter-sensing gustatory receptor neurons (GRNs) confers responsiveness to L-canavanine. Canavanine 136-148 Gustatory receptor 8a Drosophila melanogaster 25-29 26568264-7 2015 Co-expression of GR8a, GR66a and GR98b in Drosophila S2 cells induces an L-canavanine-activated nonselective cation conductance. Canavanine 73-85 Gustatory receptor 8a Drosophila melanogaster 17-21