PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11230720-0	2001	L-canavanine, a selective inhibitor of inducible NO synthase, increases plasma endothelin-1 concentrations in dogs with endotoxic shock.	Canavanine	0-12	endothelin 1	Canis lupus familiaris	79-91	
11230720-1	2001	PURPOSE: The purpose of this article is to elucidate the effect of L-canavanine, a selective inhibitor of inducible NO synthase (iNOS), on hemodynamics, blood gas parameters, and plasma concentrations of lactate and endothelin-1 (ET-1) during endotoxic shock.	Canavanine	67-79	endothelin 1	Canis lupus familiaris	216-228	
11230720-1	2001	PURPOSE: The purpose of this article is to elucidate the effect of L-canavanine, a selective inhibitor of inducible NO synthase (iNOS), on hemodynamics, blood gas parameters, and plasma concentrations of lactate and endothelin-1 (ET-1) during endotoxic shock.	Canavanine	67-79	endothelin 1	Canis lupus familiaris	230-234	
11230720-7	2001	CONCLUSIONS: This study suggests that L-canavanine induces tissue hypoperfusion and ischemia with concomitant hypersecretion of ET-1 in dogs with endotoxic shock.	Canavanine	38-50	endothelin 1	Canis lupus familiaris	128-132