PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1612105-2 1992 L-Canavanine, a selective inhibitor of inducible nitric oxide synthase, augmented contractile responses in vessels from endotoxin, but not saline-pretreated animals. Canavanine 0-12 nitric oxide synthase 2 Rattus norvegicus 39-70 23624824-4 2013 L-canavanine, a selective iNOS inhibitor, partly blocked CoCl2-induced cytotoxicity, apoptosis and mitochondrial insult. Canavanine 0-12 nitric oxide synthase 2 Rattus norvegicus 26-30 9154870-2 1997 In the present study, we evaluated the effects of L-canavanine, a selective iNOS inhibitor, in an animal model of septic shock, with a particular focus on tissue oxidative metabolism and organ functions. Canavanine 50-62 nitric oxide synthase 2 Rattus norvegicus 76-80 24777576-4 2014 To explore whether alpha-synuclein oligomerization was associated with S-nitrosylation of PDI, we made the rat brain slice model of manganism and pretreated slices with L-Canavanine, a selective iNOS inhibitor. Canavanine 169-181 nitric oxide synthase 2 Rattus norvegicus 195-199 10030795-3 1999 The use of L-canavanine, a selective inhibitor of iNOS, might be more suitable. Canavanine 11-23 nitric oxide synthase 2 Rattus norvegicus 50-54 10030795-15 1999 In conclusion, in a rodent model of endotoxinic shock, the continuous infusion of L-canavanine, a selective iNOS inhibitor, improved the systemic hemodynamic parameters and the intracellular bio-energetic patterns estimated by in vivo 31P MRS. To the contrary, the continuous infusion of both constitutive and inducible NOS inhibitor L-NMMA was not followed by the same achievement. Canavanine 82-94 nitric oxide synthase 2 Rattus norvegicus 108-112 7535234-2 1994 In contrast, intravenous infusion of L-canavanine (100 mg/kg), reported to be a selective inhibitor of inducible NO synthase in vitro, 60 min and 180 min after lipopolysaccharide challenge, produced an increase in mean arterial pressure and reversed the lipopolysaccharide induced hypotension. Canavanine 37-49 nitric oxide synthase 2 Rattus norvegicus 103-124