PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12150944-0 2002 Arginine antimetabolite L-canavanine induces apoptotic cell death in human Jurkat T cells via caspase-3 activation regulated by Bcl-2 or Bcl-xL. Canavanine 24-36 BCL2 apoptosis regulator Homo sapiens 128-133 12150944-6 2002 These results demonstrate that the cytotoxic effect of L-canavanine on Jurkat T cells is attributable to the induced apoptosis and that L-canavanine-induced apoptosis is mediated by a cytochrome c-independent caspase-3 activation pathway that can be interrupted by Bcl-2 or Bcl-xL. Canavanine 136-148 BCL2 apoptosis regulator Homo sapiens 265-270