PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17177822-7 1996 Co-incubation of serum and wound fluid resulted in an ethylenediamine tetraacetic acid-inhibitable degradation of serum insulin-like growth factor binding protein-3, suggesting the presence of an insulin-like growth factor binding protein-3 degrading activity in wound fluid. Edetic Acid 54-86 insulin like growth factor binding protein 3 Homo sapiens 120-164 18294961-7 2008 CONCLUSION: Total IGF-1 and IGFBP-3 levels are stable in whole blood collected in EDTA tubes at room temperature up till 7 days, allowing a delay in blood processing to reduce costs in large multi-center studies. Edetic Acid 82-86 insulin like growth factor binding protein 3 Homo sapiens 28-35 15013428-4 2004 Processed ADAM28s digested insulin-like growth factor binding protein-3 (IGFBP-3) in both free and complex forms with IGF-I or IGF-II, and the digestion was prevented with EDTA, 1,10-phenanthroline, KB-R7785, tissue inhibitor of metalloproteinases-3 (TIMP-3), and TIMP-4. Edetic Acid 172-176 insulin like growth factor binding protein 3 Homo sapiens 27-71 15013428-4 2004 Processed ADAM28s digested insulin-like growth factor binding protein-3 (IGFBP-3) in both free and complex forms with IGF-I or IGF-II, and the digestion was prevented with EDTA, 1,10-phenanthroline, KB-R7785, tissue inhibitor of metalloproteinases-3 (TIMP-3), and TIMP-4. Edetic Acid 172-176 insulin like growth factor binding protein 3 Homo sapiens 73-80 17177822-7 1996 Co-incubation of serum and wound fluid resulted in an ethylenediamine tetraacetic acid-inhibitable degradation of serum insulin-like growth factor binding protein-3, suggesting the presence of an insulin-like growth factor binding protein-3 degrading activity in wound fluid. Edetic Acid 54-86 insulin like growth factor binding protein 3 Homo sapiens 196-240 7523391-4 1994 Initial studies using IG-FBP-3-substrate zymography identified several IGFBP-3-degrading proteases with M(r) 52,000-72,000, which were inhibitable by EDTA and were shifted to lower M(r) species after treatment of conditioned medium with an organomercurial, suggesting that they might represent one or more of the matrix metalloproteinases (MMPs). Edetic Acid 150-154 insulin like growth factor binding protein 3 Homo sapiens 71-78 1379257-9 1992 IGFBP-3 proteolytic activity in postoperative sera was markedly inhibited by antipain, Na-p-tosyl-L-lysine chloromethyl ketone, phenylmethylsulfonylfluoride, aprotinin, o-phenanthroline, and EDTA, but not by leupeptin or N-tosyl-L-phenylalanine chloromethyl ketone. Edetic Acid 191-195 insulin like growth factor binding protein 3 Homo sapiens 0-7