PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26218418-6 2015 SUMMARY: A growing body of work demonstrates that nutrients present in high-fat foods (phosphatidylcholine, choline and L-carnitine) can be metabolized by the gut microbial enzymes to generate trimethylamine, which is then further metabolized by the host enzyme FMO3 to produce proatherogenic TMAO. trimethylamine 193-207 flavin containing monooxygenase 3 Mus musculus 262-266 33513464-0 2021 In vivo drug interactions of itopride and trimethylamine mediated by flavin-containing monooxygenase 3 in humanized-liver mice. trimethylamine 42-56 flavin containing monooxygenase 3 Mus musculus 69-102 31070450-1 2019 Objective- FMO (flavin-containing monooxygenase) 3 converts bacterial-derived trimethylamine to trimethylamine N-oxide (TMAO), an independent risk factor for cardiovascular disease. trimethylamine 78-92 flavin containing monooxygenase 3 Mus musculus 16-50 34945482-1 2021 Trimethylamine oxide (TMAO) originates from trimethylamine (TMA), which is oxidized in the liver by hepatic flavin-containing monooxygenases (FMO3). trimethylamine 44-58 flavin containing monooxygenase 3 Mus musculus 142-146 31251986-1 2019 Trimethylamine-N-oxide (TMAO) is a metabolite derived from trimethylamine (TMA), which is first produced by gut microbiota and then oxidized by flavin-containing monooxygenase 3 (FMO3) in the liver. trimethylamine 59-73 flavin containing monooxygenase 3 Mus musculus 144-177 31251986-1 2019 Trimethylamine-N-oxide (TMAO) is a metabolite derived from trimethylamine (TMA), which is first produced by gut microbiota and then oxidized by flavin-containing monooxygenase 3 (FMO3) in the liver. trimethylamine 59-73 flavin containing monooxygenase 3 Mus musculus 179-183 23312283-3 2013 We demonstrate that two flavin mono-oxygenase family members, FMO1 and FMO3, oxidize trimethylamine (TMA), derived from gut flora metabolism of choline, to TMAO. trimethylamine 85-99 flavin containing monooxygenase 3 Mus musculus 71-75 23312283-3 2013 We demonstrate that two flavin mono-oxygenase family members, FMO1 and FMO3, oxidize trimethylamine (TMA), derived from gut flora metabolism of choline, to TMAO. trimethylamine 101-104 flavin containing monooxygenase 3 Mus musculus 71-75 23177478-6 2013 The two-step trimethylamine biosynthesis pathway involves synergy between commensal microflora and a sex-dependent liver enzyme, flavin-containing monooxygenase 3 (FMO3), which oxidizes trimethylamine. trimethylamine 13-27 flavin containing monooxygenase 3 Mus musculus 129-162 23177478-6 2013 The two-step trimethylamine biosynthesis pathway involves synergy between commensal microflora and a sex-dependent liver enzyme, flavin-containing monooxygenase 3 (FMO3), which oxidizes trimethylamine. trimethylamine 13-27 flavin containing monooxygenase 3 Mus musculus 164-168 23177478-6 2013 The two-step trimethylamine biosynthesis pathway involves synergy between commensal microflora and a sex-dependent liver enzyme, flavin-containing monooxygenase 3 (FMO3), which oxidizes trimethylamine. trimethylamine 186-200 flavin containing monooxygenase 3 Mus musculus 129-162 23177478-6 2013 The two-step trimethylamine biosynthesis pathway involves synergy between commensal microflora and a sex-dependent liver enzyme, flavin-containing monooxygenase 3 (FMO3), which oxidizes trimethylamine. trimethylamine 186-200 flavin containing monooxygenase 3 Mus musculus 164-168