PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32319540-0	2020	Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK-3beta/beta-catenin signaling pathway by downregulating miR-25-3p.	Sevoflurane	0-11	phosphatase and tensin homolog	Homo sapiens	109-113	
32319540-10	2020	These data suggest that Sevo"s antitumor effects on HCC could be explained, in part, by Sevo inhibiting the miR-25-3p/PTEN/Akt/GSK-3beta/beta-catenin signaling pathway.	Sevoflurane	24-28	phosphatase and tensin homolog	Homo sapiens	118-122	
32319540-10	2020	These data suggest that Sevo"s antitumor effects on HCC could be explained, in part, by Sevo inhibiting the miR-25-3p/PTEN/Akt/GSK-3beta/beta-catenin signaling pathway.	Sevoflurane	88-92	phosphatase and tensin homolog	Homo sapiens	118-122	
32089060-0	2020	Silencing of PTEN inhibits the oxidative stress damage and hippocampal cell apoptosis induced by Sevoflurane through activating MEK1/ERK signaling pathway in infant rats.	Sevoflurane	97-108	phosphatase and tensin homolog	Homo sapiens	13-17	
32089060-6	2020	Cell apoptosis was detected by flow cytometry.Sevoflurane up-regulated PTEN expression and silencing of PTEN activates MEK1/ERK signaling pathway in hippocampal tissues and cells of infant rats.	Sevoflurane	46-57	phosphatase and tensin homolog	Homo sapiens	71-75	
32089060-6	2020	Cell apoptosis was detected by flow cytometry.Sevoflurane up-regulated PTEN expression and silencing of PTEN activates MEK1/ERK signaling pathway in hippocampal tissues and cells of infant rats.	Sevoflurane	46-57	phosphatase and tensin homolog	Homo sapiens	104-108	
32089060-7	2020	Silencing of PTEN alleviated hippocampal tissue pathological status and inhibited sevoflurane-induced cell apoptosis in hippocampal tissues of infant rats.	Sevoflurane	82-93	phosphatase and tensin homolog	Homo sapiens	13-17	
32089060-9	2020	Silencing of PTEN inhibited sevoflurane-induced apoptosis after OS damage in hippocampal cells of infant rats.	Sevoflurane	28-39	phosphatase and tensin homolog	Homo sapiens	13-17	
32089060-10	2020	Silencing of PTEN reduced sevoflurane-induced OS damage in hippocampal cells of infant rats.Our study demonstrates that PTEN silencing inhibits the OS damage and cell apoptosis in hippocampal cells induced by Sevoflurane through activating MEK1/ERK signaling pathway in infant rats.	Sevoflurane	26-37	phosphatase and tensin homolog	Homo sapiens	13-17	
31190353-9	2019	Besides, SEVO enhanced phosphatase and tensin homolog (PTEN) expression, and phosphorylated expression of phosphatidylinositol 3 kinase (PI3K), and protein kinase B (AKT) was eliminated by SEVO.	Sevoflurane	9-13	phosphatase and tensin homolog	Homo sapiens	23-53	
31190353-9	2019	Besides, SEVO enhanced phosphatase and tensin homolog (PTEN) expression, and phosphorylated expression of phosphatidylinositol 3 kinase (PI3K), and protein kinase B (AKT) was eliminated by SEVO.	Sevoflurane	9-13	phosphatase and tensin homolog	Homo sapiens	55-59	
29311820-8	2017	The expression of microtubule-associated protein 1 light chain 3 (LC3)-II, Beclin-1 and phosphatase and tensin homolog on chromosome 10 (PTEN) were increased in the 3.5% sevoflurane group, while Sequestosome 1 (P62/SQSTM1), phospho-protein kinase B/protein kinase B (p-Akt/Akt) and mammalian target of rapamycin (mTOR) were decreased.	Sevoflurane	170-181	phosphatase and tensin homolog	Homo sapiens	137-141	
32089060-10	2020	Silencing of PTEN reduced sevoflurane-induced OS damage in hippocampal cells of infant rats.Our study demonstrates that PTEN silencing inhibits the OS damage and cell apoptosis in hippocampal cells induced by Sevoflurane through activating MEK1/ERK signaling pathway in infant rats.	Sevoflurane	209-220	phosphatase and tensin homolog	Homo sapiens	13-17