PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26137236-1 2015 The aim of the present study was to investigate the roles of Rho protein A (RhoA) and Rho kinases 2 (ROCK2) in the memory dysfunction of adult rats exposed to sevoflurane at postnatal days 7-9 (P7-9). Sevoflurane 159-170 Rho-associated coiled-coil containing protein kinase 2 Rattus norvegicus 101-106 26137236-14 2015 RhoA and ROCK2 played important roles in the impairment of learning and memory of adults rats exposed to sevoflurane at the postnatal early stage. Sevoflurane 105-116 Rho-associated coiled-coil containing protein kinase 2 Rattus norvegicus 9-14 12960549-3 2003 This study is designed to examine the possible inhibitory effects of sevoflurane on the Rho/Rho-kinase pathway by measuring guanosine 5"-[gamma-thio]triphosphate (GTP gamma S)-stimulated contraction and translocation of RhoA (one of the three Rho subtypes) and Rock-2 (one of the two Rho-kinase subtypes) from the cytosol to the membrane in rat aortic smooth muscle. Sevoflurane 69-80 Rho-associated coiled-coil containing protein kinase 2 Rattus norvegicus 261-267 12960549-8 2003 Sevoflurane (1.7, 3.4, and 5.1%) concentration dependently inhibited the GTP gamma S-induced constriction of rat aortic smooth muscle with a reduction of constriction of 52-75% (P < 0.01, n = 8), and attenuated the translocation of RhoA and Rock-2 by 31-66% and 34-78%, respectively (P < 0.05-0.01, respectively; n = 4). Sevoflurane 0-11 Rho-associated coiled-coil containing protein kinase 2 Rattus norvegicus 244-250