PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2542235-0 1989 Localization of the active center of nitroxide radical reduction in rat liver microsomes: its relation to cytochrome P-450 and membrane fluidity. Hydroxylamine 37-46 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 106-122 15964563-3 2005 N(omega)-hydroxy-nor-L-arginine- (x=2) and hydroxylamine-induced relaxations were blunted by a NO scavenger and by inhibitors of the guanylyl cyclase pathway, but not by NO synthase or cytochrome P(450) inhibitors (except 7-ethoxyresorufin). Hydroxylamine 43-56 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 185-202 2542235-4 1989 Thus, the nitroxide radicals of the SLSs and TEMPOL seem to be reduced by the combined action of NADPH-cytochrome P-450 reductase and cytochrome P-450. Hydroxylamine 10-19 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 103-119 7099146-3 1982 This reaction was demonstrated to be mediated by cytochrome P-450 as suggested by induction experiments using phenobarbital, which markedly enhanced the production of this nitroxide, and by the inhibition of this monooxygenase by metyrapone, which depressed the formation of this free radical. Hydroxylamine 172-181 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 49-65 2996591-9 1985 The formed hydroxylamine then uncouples the cytochrome P-450 system to generate superoxide and hydrogen peroxide. Hydroxylamine 11-24 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 44-60 6095355-3 1984 This hydroxylamine is then further oxidized to the nitroxyl free radical norcocaine nitroxide by rat brain cytochrome P-450. Hydroxylamine 5-18 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 107-123 7445522-14 1980 The cytochrome P-450 mediated oxidation of methylformylhydrazine to a hydroxylamine derivative and further to a nitrosamide, is discussed in relation to its importance for the biological action of the hydrazine. Hydroxylamine 70-83 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 4-20 7132955-4 1982 Previous work has shown that the 14C-labeled material spontaneously released from 14C-labeled cytochrome P-450 is in the form of oxalic acid, and that the latter is derived from a hydroxylamine-labile adduct of chloramphenicol and cytochrome P-450 [Biochem. Hydroxylamine 180-193 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 231-247 32561320-0 2020 Unexpected rapid aerobic transformation of 2,2,6,6-tetraethyl-4-oxo(piperidin-1-yloxyl) radical by cytochrome P450 in the presence of NADPH: evidence against a simple reduction of the nitroxide moiety to the hydroxylamine. Hydroxylamine 184-193 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 99-114 38075-4 1979 The hydroxylamine-nitro-oxidation appears to be dependent on cytochrome P-450, as the reaction was induced by phenobarbital pretreatment and inhibited by carbon monoxide and 2,4-dichloro-6-phenylphenoxyethylamine. Hydroxylamine 4-17 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 61-77 32561320-0 2020 Unexpected rapid aerobic transformation of 2,2,6,6-tetraethyl-4-oxo(piperidin-1-yloxyl) radical by cytochrome P450 in the presence of NADPH: evidence against a simple reduction of the nitroxide moiety to the hydroxylamine. Hydroxylamine 208-221 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 99-114