PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32061592-6	2020	LA with uncycled N-methyl scaffold in the side chain (procaine, tetracaine and lidocaine) had a better strength of drug-H1R affinity than that for LA with cycled N atom (bupivacaine and ropivacaine) by the molecular docking assay and equilibrium dissociation constant (KD values) obtained from the cell membrane chromatography (CMC) relative standard method.	3-O-methyl-alpha-methyldopamine	17-25	histamine receptor H1	Homo sapiens	120-123	
32061592-10	2020	This study supported a key role of H1R in LA-induced angioedema, and suggested that in the design of LA structure, the ring formation of the N-methyl scaffold on the side chain can properly avoid the angioedema.	3-O-methyl-alpha-methyldopamine	141-149	histamine receptor H1	Homo sapiens	35-38