PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3500229-7 1987 Production of Eo-CSF in vitro was inhibited by hydrocortisone or cyclosporin A. Hydrocortisone 47-61 colony stimulating factor 2 Homo sapiens 17-20 6297360-5 1982 The relationship between CSF opioid activity and HPA axis activity, as reflected by urinary free cortisol excretion, supports the notion of important physiologic relationships between these systems and raises the issue of a role for the endogenous opioid system in the abnormal activation of this system in depression. Hydrocortisone 97-105 colony stimulating factor 2 Homo sapiens 25-28 2943770-4 1986 Moreover, a significantly negative correlation was found between the CSF norepinephrine level and the pre-dexamethasone 4 p.m. plasma cortisol level in those endogenous depressed patients who had a positive DST response. Hydrocortisone 134-142 colony stimulating factor 2 Homo sapiens 69-72 6601023-5 1983 Moreover, addition of hydrocortisone to T-lymphocyte- and phagocyte-depleted bone marrow cells also increased the number of neutrophil colonies and decreased macrophage colonies in the presence of CSF. Hydrocortisone 22-36 colony stimulating factor 2 Homo sapiens 197-200 23453639-9 2013 Exposure to interpersonal violence as a child showed a negative correlation with CSF cortisol/DHEAS ratio adjusted for age, gender and depression severity in a regression analysis. Hydrocortisone 85-93 colony stimulating factor 2 Homo sapiens 81-84 30881301-7 2019 Subjects with dementia and Mild Cognitive Impairment (MCI) due to AD have been found to have higher CSF cortisol levels than cognitively healthy controls. Hydrocortisone 104-112 colony stimulating factor 2 Homo sapiens 100-103 28846166-0 2017 Cortisol inhibits CSF2 and CSF3 via DNA methylation and inhibits invasion in first-trimester trophoblast cells. Hydrocortisone 0-8 colony stimulating factor 2 Homo sapiens 18-22 28846166-6 2017 RESULTS: Cortisol inhibited expression of CSF2 (GM-CSF) and CSF3 (G-CSF) in trophoblast cells. Hydrocortisone 9-17 colony stimulating factor 2 Homo sapiens 42-46 28846166-6 2017 RESULTS: Cortisol inhibited expression of CSF2 (GM-CSF) and CSF3 (G-CSF) in trophoblast cells. Hydrocortisone 9-17 colony stimulating factor 2 Homo sapiens 48-54 26705843-8 2016 Cluster analysis then defined two distinct clusters, such that individuals in cluster 1 had highly positive PC1 scores and relatively higher levels of CSF cortisol, progesterone, estradiol, testosterone, brain derived neurotrophic factor (BDNF), and S100b; this group also had higher serum cortisol and lower serum BDNF. Hydrocortisone 155-163 colony stimulating factor 2 Homo sapiens 151-154 24736562-3 2014 We found that primary human corneal epithelial cells (PHCEC), fibroblasts (PHKF) and allogeneic macrophages (M1, GM-CSF; M2, M-CSF) were capable of generating cortisol (M1>PHKF>M2>PHCEC) but in corneal cells, this was independent of Toll-like receptor (TLR) activation. Hydrocortisone 159-167 colony stimulating factor 2 Homo sapiens 113-119 27567115-14 2016 In male suicide attempters, the CSF testosterone/cortisol ratio showed a significant positive correlation with both impulsivity and aggressiveness. Hydrocortisone 49-57 colony stimulating factor 2 Homo sapiens 32-35 9845380-10 1998 These results indicate that lower concentrations of hydrocortisone inhibit GM-CSF production from normal human blood MNCs and T cells entirely by inhibiting the expression of GM-CSF mRNA, and higher concentrations of hydrocortisone inhibit by a combined effect of inhibiting the expression of GM-CSF mRNA and decreasing the lymphocyte count. Hydrocortisone 52-66 colony stimulating factor 2 Homo sapiens 175-181 20451611-5 2010 A significant increase in cortisol levels was found in prefrontal cortex and CSF samples from subjects with schizophrenia. Hydrocortisone 26-34 colony stimulating factor 2 Homo sapiens 77-80 19062105-5 2009 Plasma cortisol levels at 8:00 a.m., 4:00 p.m. and 11:00 p.m. were analysed in relation to CSF 5-HIAA. Hydrocortisone 7-15 colony stimulating factor 2 Homo sapiens 91-94 19062105-8 2009 In male suicide victims (n=6), the serum cortisol level at 4:00 p.m. showed a significant positive correlation with CSF 5-HIAA. Hydrocortisone 41-49 colony stimulating factor 2 Homo sapiens 116-119 11258049-10 2001 TNF-alpha and GM-CSF were significantly more produced, even in the presence of hydrocortisone, whereas the synthesis of IL-10 was diminished by fixed Igs. Hydrocortisone 79-93 colony stimulating factor 2 Homo sapiens 14-20 10460758-5 1999 Hydrocortisone inhibited GM-CSF release in stimulated PBEC with a concentration that produces 50% inhibition of maximum effect (IC(1/2)max) of 5.0 x 10(-8) M. In the presence of glycyrrhetinic acid, the potency of hydrocortisone was increased approximately 33-fold (IC(1/2)max with glycyrrhetinic acid, 1.5 x 10(-9) M). Hydrocortisone 0-14 colony stimulating factor 2 Homo sapiens 25-31 9845380-0 1998 Hydrocortisone inhibits granulocyte-macrophage colony-stimulating factor production from normal human peripheral blood mononuclear cells and CD3+ T cells. Hydrocortisone 0-14 colony stimulating factor 2 Homo sapiens 24-72 9845380-8 1998 Administering hydrocortisone at 5, 50, and 250 pg/dL decreased GM-CSF production (p < 0.003) in LPS- or PHA-stimulated MNC cultures and in PHA-stimulated T-cell cultures. Hydrocortisone 14-28 colony stimulating factor 2 Homo sapiens 63-69 9845380-9 1998 PHA (not tested with LPS)-stimulated GM-CSF messenger RNA (mRNA) expression was blocked by hydrocortisone. Hydrocortisone 91-105 colony stimulating factor 2 Homo sapiens 37-43 20181121-2 2010 CSF cortisol levels more closely reflect brain exposure to cortisol, but there are no studies of CSF cortisol levels in delirium. Hydrocortisone 4-12 colony stimulating factor 2 Homo sapiens 0-3 20181121-11 2010 CONCLUSIONS: These findings support an association between higher CSF cortisol levels and delirium. Hydrocortisone 70-78 colony stimulating factor 2 Homo sapiens 66-69 8804472-2 1995 In fact, our previous studies have shown that GM-CSF may stimulate cortisol and GH release. Hydrocortisone 67-75 colony stimulating factor 2 Homo sapiens 46-52 9749865-6 1998 Hydrocortisone significantly suppressed the production of IL-6, IL-8, and GM-CSF by TCCs from AH of VKH patients. Hydrocortisone 0-14 colony stimulating factor 2 Homo sapiens 74-80 8728354-10 1996 HC inhibited the secretion of GM-CSF and LIF induced by IL-1. Hydrocortisone 0-2 colony stimulating factor 2 Homo sapiens 30-36 9845380-10 1998 These results indicate that lower concentrations of hydrocortisone inhibit GM-CSF production from normal human blood MNCs and T cells entirely by inhibiting the expression of GM-CSF mRNA, and higher concentrations of hydrocortisone inhibit by a combined effect of inhibiting the expression of GM-CSF mRNA and decreasing the lymphocyte count. Hydrocortisone 52-66 colony stimulating factor 2 Homo sapiens 75-81 9845380-10 1998 These results indicate that lower concentrations of hydrocortisone inhibit GM-CSF production from normal human blood MNCs and T cells entirely by inhibiting the expression of GM-CSF mRNA, and higher concentrations of hydrocortisone inhibit by a combined effect of inhibiting the expression of GM-CSF mRNA and decreasing the lymphocyte count. Hydrocortisone 52-66 colony stimulating factor 2 Homo sapiens 175-181 9537772-11 1998 In contrast, hydrocortisone, but not cetirizine, reduced GM-CSF and IL-8 release. Hydrocortisone 13-27 colony stimulating factor 2 Homo sapiens 57-63 9185525-7 1997 Hydrocortisone reduced GM-CSF gene expression and protein release in both atopic and control keratinocytes. Hydrocortisone 0-14 colony stimulating factor 2 Homo sapiens 23-29 8774352-6 1996 In contrast to the stimulatory effect of GM-CSF, hydrocortisone, dexamethasone or all-trans-retinoic acid at 1 x 10(-7) to 1 x 10(-5) M inhibited the constitutive expression of activin A and greatly suppressed the GM-CSF-stimulated production. Hydrocortisone 49-63 colony stimulating factor 2 Homo sapiens 214-220 8857112-3 1995 Hydrocortisone decreased the level of Elo-CSF in the CM. Hydrocortisone 0-14 colony stimulating factor 2 Homo sapiens 42-45 8857112-8 1995 Eo-CSF production is inhibited by hydrocortisone. Hydrocortisone 34-48 colony stimulating factor 2 Homo sapiens 3-6 8114512-8 1994 Treatment of lung fragments in vitro for 18 h with hydrocortisone (HC) inhibited the production of GM-CSF dose-dependently. Hydrocortisone 51-65 colony stimulating factor 2 Homo sapiens 99-105 8114512-9 1994 Maximal inhibition of GM-CSF production was 72.8 +/- 4.0% at a concentration of 10(-6) M hydrocortisone (n = 5), and the molar concentration of HC that inhibited of GM-CSF production by lung tissue by 50% (IC50) was approximately 4.5 x 10(-7) M. Kinetic studies revealed that a 6 h preincubation with the drug was required for 50% inhibition of GM-CSF production. Hydrocortisone 89-103 colony stimulating factor 2 Homo sapiens 22-28 1296456-5 1992 Both cortisol and GH significantly increased in response to GM-CSF, while PRL, and melatonin were not influenced. Hydrocortisone 5-13 colony stimulating factor 2 Homo sapiens 60-66 8356399-3 1993 We found that hydrocortisone stimulated cell proliferation but inhibited the differentiation of TEC and significantly reduced the production of interleukin-1 alpha, interleukin-6 and granulocyte-macrophage colony stimulating factor. Hydrocortisone 14-28 colony stimulating factor 2 Homo sapiens 183-231