PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23846683-1 2013 Covalently linked carboxyl-terminal segments of the beta-amyloid peptide (Abeta) were tested for their qualification as minimal conformational epitopes of the naturally occurring human autoantibodies against beta-amyloid (nAbs-Abeta). nabs 222-226 amyloid beta precursor protein Homo sapiens 52-72 23846683-1 2013 Covalently linked carboxyl-terminal segments of the beta-amyloid peptide (Abeta) were tested for their qualification as minimal conformational epitopes of the naturally occurring human autoantibodies against beta-amyloid (nAbs-Abeta). nabs 222-226 amyloid beta precursor protein Homo sapiens 227-232 23846683-2 2013 nAbs-Abeta specifically recognize the toxic oligomers of Abeta and not the monomeric or the fibrillar forms of Abeta. nabs 0-4 amyloid beta precursor protein Homo sapiens 5-10 23846683-2 2013 nAbs-Abeta specifically recognize the toxic oligomers of Abeta and not the monomeric or the fibrillar forms of Abeta. nabs 0-4 amyloid beta precursor protein Homo sapiens 57-62 23846683-2 2013 nAbs-Abeta specifically recognize the toxic oligomers of Abeta and not the monomeric or the fibrillar forms of Abeta. nabs 0-4 amyloid beta precursor protein Homo sapiens 57-62 23846683-7 2013 Synthetic peptide epitopes with high affinities for nAbs-Abeta are needed to identify the physiological roles of nAbs-Abeta and are promising epitopes for vaccination experiments. nabs 52-56 amyloid beta precursor protein Homo sapiens 57-62 23846683-7 2013 Synthetic peptide epitopes with high affinities for nAbs-Abeta are needed to identify the physiological roles of nAbs-Abeta and are promising epitopes for vaccination experiments. nabs 52-56 amyloid beta precursor protein Homo sapiens 118-123 23846683-7 2013 Synthetic peptide epitopes with high affinities for nAbs-Abeta are needed to identify the physiological roles of nAbs-Abeta and are promising epitopes for vaccination experiments. nabs 113-117 amyloid beta precursor protein Homo sapiens 57-62 23846683-7 2013 Synthetic peptide epitopes with high affinities for nAbs-Abeta are needed to identify the physiological roles of nAbs-Abeta and are promising epitopes for vaccination experiments. nabs 113-117 amyloid beta precursor protein Homo sapiens 118-123 22903668-7 2012 This chapter summarizes our current knowledge on NAbs against Abeta. nabs 49-53 amyloid beta precursor protein Homo sapiens 62-67 23209707-3 2012 Previously, we and others have shown that natural human IgGs (NAbs) target diverse Abeta conformers and have therapeutic potential. nabs 62-66 amyloid beta precursor protein Homo sapiens 83-88 23209707-5 2012 Importantly, NAbs also recognized Abeta extracted from the water-soluble phase of human AD brain, including species that migrated on denaturing PAGE as SDS-stable dimers. nabs 13-17 amyloid beta precursor protein Homo sapiens 34-39 23209707-7 2012 The antibody"s lack of reactivity against a linear sequence epitope was confirmed by our ability to isolate anti-Abeta NAbs from intravenous immunoglobulin using affinity matrices, immunoglobulin light chain fibrils and Cibacron blue, which had no sequence similarity with the peptide. nabs 119-123 amyloid beta precursor protein Homo sapiens 113-118 23209707-8 2012 These findings suggest that further investigations on the molecular basis and the therapeutic/diagnostic potential of anti-Abeta NAbs are warranted. nabs 129-133 amyloid beta precursor protein Homo sapiens 123-128 20329802-6 2010 Beyond the occurrence of nAbs-Abeta, evidence for several other mechanisms associated with IVIG in AD has been reported in preclinical experiments and clinical studies. nabs 25-29 amyloid beta precursor protein Homo sapiens 30-35 33523832-3 2021 NAbs-Abeta levels in plasma and cerebrospinal fluid (CSF) were tested according to their epitopes. nabs 0-4 amyloid beta precursor protein Homo sapiens 5-10 33523832-4 2021 Levels of NAbs targeting the amino terminus of Abeta increased, and those targeting the mid-domain of Abeta decreased in both CSF and plasma in AD patients. nabs 10-14 amyloid beta precursor protein Homo sapiens 47-52 33523832-5 2021 Higher plasma levels of NAbs targeting the amino terminus of Abeta and lower plasma levels of NAbs targeting the mid-domain of Abeta were associated with higher brain amyloidosis at baseline and faster cognitive decline during follow-up. nabs 24-28 amyloid beta precursor protein Homo sapiens 61-66 33523832-5 2021 Higher plasma levels of NAbs targeting the amino terminus of Abeta and lower plasma levels of NAbs targeting the mid-domain of Abeta were associated with higher brain amyloidosis at baseline and faster cognitive decline during follow-up. nabs 94-98 amyloid beta precursor protein Homo sapiens 127-132 27802290-3 2016 Therefore, we explored nAbs against alpha-synuclein (alphaS), tau and beta-amyloid (Abeta) in PDD compared to cognitively normal PD patients. nabs 23-27 amyloid beta precursor protein Homo sapiens 84-89 27802290-8 2016 Though, due to a high interassay coefficient of variability and the exclusion of many samples below the limit of detection, conclusions for nAbs-Abeta are only conditionally possible. nabs 140-144 amyloid beta precursor protein Homo sapiens 145-150