PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25961225-8 2010 Other DHEA and testosterone-derived metabolites, namely epiandrosterone and 5alpha-androstane-3beta,17beta-diol, are also substrates for the CYP7B1 and their 7alpha-hydroxylated products were also converted into the 7beta epimer by the 11beta-HSD1. 17beta-diol 100-111 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 141-147 17825335-4 2007 Among testosterone metabolites, 5alpha-androstane-3beta,17beta-diol (Adiol) is a substrate for the cytochrome P450 7B1 which produces 5alpha-androstane-3beta,7alpha,17beta-triol (7alpha-Adiol). 17beta-diol 56-67 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 99-118 18331353-0 2008 CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol--potential role(s) for estrogen signaling. 17beta-diol 81-92 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 0-6 18331353-1 2008 CYP7B1, a cytochrome P450 enzyme, metabolizes several steroids involved in hormonal signaling including 5alpha-androstane-3beta,17beta-diol (3beta-Adiol), an estrogen receptor agonist, and dehydroepiandrosterone, a precursor for sex hormones. 17beta-diol 128-139 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 0-6 19732851-0 2009 CYP7B1-mediated metabolism of 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol): a novel pathway for potential regulation of the cellular levels of androgens and neurosteroids. 17beta-diol 55-66 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 0-6 19732851-1 2009 The current study presents data indicating that 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol) undergoes a previously unknown metabolism into hydroxymetabolites, catalyzed by CYP7B1. 17beta-diol 73-84 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 180-186 17639508-2 2007 Cytochrome P450 (CYP) 7B1 is expressed within the prostate and may determine the levels of the natural estrogen receptor beta (ERbeta) ligand 5alpha-androstane-3beta,17beta-diol (3betaAdiol) available and hence affect the regulation of prostate proliferation. 17beta-diol 166-177 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 0-25 16630558-8 2006 CYP7B1 was stimulated by synthetic ER agonists but suppressed by 17beta-estradiol and 5alpha-androstane-3beta,17beta-diol in LNCaP cells. 17beta-diol 110-121 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 0-6