PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11262086-1	2001	Previous studies have shown that flavones bind to P-glycoprotein (Pgp) with higher affinity than isoflavones, flavanones, and glycosylated derivatives.	Isoflavones	97-108	ATP binding cassette subfamily B member 1	Homo sapiens	66-69	
15828450-2	2005	This study demonstrates that some putative flavonoids, i.e., flavonols (quercetin and kaempferol) and isoflavones (genistein and daidzein) markedly increase the sensitivity of the multidrug-resistant human cervical carcinoma KB-V1 cells (high Pgp expression) to vinblastine and paclitaxel dose-dependently, and also decrease the relative resistance of these anti-cancer-drugs in KB-V1 cells.	Isoflavones	102-113	ATP binding cassette subfamily B member 1	Homo sapiens	243-246	
15828450-5	2005	The flavonols increased the inhibitory effectiveness of Pgp activity in MDR KB-V1 cells more than isoflavones.	Isoflavones	98-109	ATP binding cassette subfamily B member 1	Homo sapiens	56-59	
11262086-1	2001	Previous studies have shown that flavones bind to P-glycoprotein (Pgp) with higher affinity than isoflavones, flavanones, and glycosylated derivatives.	Isoflavones	97-108	ATP binding cassette subfamily B member 1	Homo sapiens	50-64	
23720244-0	2013	Interaction of CJY, an isoflavone, with ATPase of P-glycoprotein in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.	Isoflavones	23-33	ATP binding cassette subfamily B member 1	Homo sapiens	50-64	
23720244-1	2013	OBJECTIVES: The previous study reported CJY, an isoflavone, can reverse P-glycoprotein (P-gp)-mediated multidrug-resistance (MDR) in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.	Isoflavones	48-58	ATP binding cassette subfamily B member 1	Homo sapiens	72-86	
23720244-1	2013	OBJECTIVES: The previous study reported CJY, an isoflavone, can reverse P-glycoprotein (P-gp)-mediated multidrug-resistance (MDR) in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.	Isoflavones	48-58	ATP binding cassette subfamily B member 1	Homo sapiens	88-92	
22914566-6	2012	A negative regulation of hMDR1 gene with multiple transcription factors by this isoflavone may provide a novel molecular mechanism for MDR modulation.	Isoflavones	80-90	ATP binding cassette subfamily B member 1	Homo sapiens	25-30	
17637197-0	2007	CJY, an isoflavone, reverses P-glycoprotein-mediated multidrug-resistance in doxorubicin-resistant human myelogenous leukaemia (K562/DOX) cells.	Isoflavones	8-18	ATP binding cassette subfamily B member 1	Homo sapiens	29-43	
17637197-1	2007	In an effort to develop safe and effective multidrug-resistance (MDR) reversing agents, the effect of CJY, an isoflavone, on the P-glycoprotein (P-gp) function and P-gp-mediated MDR was evaluated in doxorubicin-resistant human myelogenous leukaemia (K562/DOX) cells.	Isoflavones	110-120	ATP binding cassette subfamily B member 1	Homo sapiens	129-143	
17637197-1	2007	In an effort to develop safe and effective multidrug-resistance (MDR) reversing agents, the effect of CJY, an isoflavone, on the P-glycoprotein (P-gp) function and P-gp-mediated MDR was evaluated in doxorubicin-resistant human myelogenous leukaemia (K562/DOX) cells.	Isoflavones	110-120	ATP binding cassette subfamily B member 1	Homo sapiens	145-149