PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19000315-15 2008 High intake of Se and isoflavones each decreased serum IGF-1 in pups at 100 and 200 days, but not in breeders. Isoflavones 22-33 insulin-like growth factor 1 Rattus norvegicus 55-60 21467133-6 2011 Although the high isoflavone content seemed to prevent the effect on circulating estradiol and IGF-1 levels and advanced puberty onset seen in the LIM group, HIM increased DMBA-DNA adducts in the mammary gland and tended to increase mammary tumorigenesis. Isoflavones 18-28 insulin-like growth factor 1 Rattus norvegicus 95-100 19000315-17 2008 In pups, the combination of high isoflavones and high selenium produced the lowest weight gain, the lowest serum leptin, and the lowest serum IGF-1 concentrations of all four diets. Isoflavones 33-44 insulin-like growth factor 1 Rattus norvegicus 142-147 17166423-0 2006 [Soy isoflavones with supplemental calcium provide protection against the loss of bone mass and influence insulin-like growth factor (IGF)-I after ovariectomy in rat]. Isoflavones 5-16 insulin-like growth factor 1 Rattus norvegicus 106-140 14969347-0 2004 Isoflavones extracted from Sophorae fructus upregulate IGF-I and TGF-beta and inhibit osteoclastogenesis in rat bone marrow cells. Isoflavones 0-11 insulin-like growth factor 1 Rattus norvegicus 55-60