PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34063981-7	2021	Isoflavone biosynthetic genes, including CHI1A, IFS1, and IFS2, showed differences in stages and expression patterns among individuals and wild-types, whereas MaT7 showed consistently higher expression levels in three mutants with increased isoflavone content at stage 1.	Isoflavones	0-10	isoflavone synthase 1	Glycine max	48-52	
15778457-2	2005	Isoflavone synthase (IFS) is a key enzyme for the formation of the isoflavones.	Isoflavones	67-78	isoflavone synthase 1	Glycine max	0-19	
15778457-2	2005	Isoflavone synthase (IFS) is a key enzyme for the formation of the isoflavones.	Isoflavones	67-78	isoflavone synthase 1	Glycine max	21-24	
15778457-6	2005	Silencing of IFS was also demonstrated throughout the entire cotyledon (in tissues distal to the transformation site) both by high-performance liquid chromatography analysis of isoflavones and by real-time reverse transcription-PCR.	Isoflavones	177-188	isoflavone synthase 1	Glycine max	13-16	
12384577-7	2002	The bottleneck for constitutive isoflavone production in Arabidopsis is, therefore, competition for flavanone between IFS and endogenous flavonol synthesis, and the flavonol pathway is reciprocally but disproportionately affected by IFS.	Isoflavones	32-42	isoflavone synthase 1	Glycine max	118-121	
12384577-7	2002	The bottleneck for constitutive isoflavone production in Arabidopsis is, therefore, competition for flavanone between IFS and endogenous flavonol synthesis, and the flavonol pathway is reciprocally but disproportionately affected by IFS.	Isoflavones	32-42	isoflavone synthase 1	Glycine max	233-236	
11027726-3	2000	Expression of a soybean isoflavone synthase (IFS) gene in Arabidopsis plants was previously shown to result in the synthesis and accumulation of the isoflavone genistein in leaf and stem tissue (Jung et al., 2000).	Isoflavones	24-34	isoflavone synthase 1	Glycine max	45-48	
11027726-8	2000	Introduction of a third gene, chalcone reductase, provided the ability to synthesize an additional substrate of IFS resulting in production of the isoflavone daidzein in this system.	Isoflavones	147-157	isoflavone synthase 1	Glycine max	112-115	
23199070-2	2012	This study was conducted to determine the effects of high-temperature stress on isoflavone concentration and expression of four key genes involved in isoflavone synthesis (i.e., CHS7, CHS8, IFS1, and IFS2) in both soybean pods and seeds during their late reproductive stage (i.e., R5-R8).	Isoflavones	150-160	isoflavone synthase 1	Glycine max	190-194	
21409550-0	2011	Metabolic engineering of isoflavone genistein in Brassica napus with soybean isoflavone synthase.	Isoflavones	25-35	isoflavone synthase 1	Glycine max	77-96	
32480858-4	2010	Genes encoding chalcone synthase 7 (CHS7), chalcone synthase 8 (CHS8) and isoflavone synthase 1 (IFS1) displayed high basal expression levels in roots compared with hypocotyls, suggesting they could be the gene family members encoding the isoenzyme that contributes the most to the principal substrate flux towards specific isoflavone synthesis in roots.	Isoflavones	74-84	isoflavone synthase 1	Glycine max	97-101	
32099739-2	2020	The expression levels of four major genes viz., CHS7, CHS8, IFS2, and IFS1 involved on isoflavones biosynthesis during seed developmental stages from R5L-R7 was seen in both MAUS-2 and JS-335 Soybean varieties.	Isoflavones	87-98	isoflavone synthase 1	Glycine max	70-74	
32099739-9	2020	Both biotic and abiotic treatments contribute to the upregulation of IFS1 and IFS2 expression, that in turn, leads to the accumulation of isoflavone in seed development as well as in suspension cultures.	Isoflavones	138-148	isoflavone synthase 1	Glycine max	69-73