PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34063981-7	2021	Isoflavone biosynthetic genes, including CHI1A, IFS1, and IFS2, showed differences in stages and expression patterns among individuals and wild-types, whereas MaT7 showed consistently higher expression levels in three mutants with increased isoflavone content at stage 1.	Isoflavones	0-10	2-hydroxyisoflavanone synthase	Glycine max	58-62	
32099739-2	2020	The expression levels of four major genes viz., CHS7, CHS8, IFS2, and IFS1 involved on isoflavones biosynthesis during seed developmental stages from R5L-R7 was seen in both MAUS-2 and JS-335 Soybean varieties.	Isoflavones	87-98	2-hydroxyisoflavanone synthase	Glycine max	60-64	
32099739-9	2020	Both biotic and abiotic treatments contribute to the upregulation of IFS1 and IFS2 expression, that in turn, leads to the accumulation of isoflavone in seed development as well as in suspension cultures.	Isoflavones	138-148	2-hydroxyisoflavanone synthase	Glycine max	78-82	
32099739-10	2020	These data further suggested that the IFS2 is the key gene responsible for the isoflavone accumulation during elicitor treatment.	Isoflavones	79-89	2-hydroxyisoflavanone synthase	Glycine max	38-42	
23617338-3	2013	Nearly complete inhibition of isoflavone synthesis was found in the cotyledons of young seedlings of transgenic plants transformed with the IFS2 transgene driven by the cotyledon-preferable lectin promoter compared with the untransformed control during the 10-day observation period, with the precursors of isoflavone synthesis being accumulated in the cotyledons of transgenic plants.	Isoflavones	30-40	2-hydroxyisoflavanone synthase	Glycine max	140-144	
23617338-3	2013	Nearly complete inhibition of isoflavone synthesis was found in the cotyledons of young seedlings of transgenic plants transformed with the IFS2 transgene driven by the cotyledon-preferable lectin promoter compared with the untransformed control during the 10-day observation period, with the precursors of isoflavone synthesis being accumulated in the cotyledons of transgenic plants.	Isoflavones	307-317	2-hydroxyisoflavanone synthase	Glycine max	140-144	
23199070-2	2012	This study was conducted to determine the effects of high-temperature stress on isoflavone concentration and expression of four key genes involved in isoflavone synthesis (i.e., CHS7, CHS8, IFS1, and IFS2) in both soybean pods and seeds during their late reproductive stage (i.e., R5-R8).	Isoflavones	150-160	2-hydroxyisoflavanone synthase	Glycine max	200-204	
20430761-12	2010	Expression of CHS7, CHS8 and IFS2 correlated with isoflavone accumulation under well-watered conditions.	Isoflavones	50-60	2-hydroxyisoflavanone synthase	Glycine max	29-33	
20430761-14	2010	The abundance of IFS1 transcripts was maintained at a constant rate, whereas IFS2 was down-regulated and highly correlated with isoflavone accumulation under both water deficit and well-watered conditions, suggesting IFS2 as a main contributor to isoflavone diminution under drought.	Isoflavones	128-138	2-hydroxyisoflavanone synthase	Glycine max	77-81	
20430761-14	2010	The abundance of IFS1 transcripts was maintained at a constant rate, whereas IFS2 was down-regulated and highly correlated with isoflavone accumulation under both water deficit and well-watered conditions, suggesting IFS2 as a main contributor to isoflavone diminution under drought.	Isoflavones	247-257	2-hydroxyisoflavanone synthase	Glycine max	77-81	
20430761-14	2010	The abundance of IFS1 transcripts was maintained at a constant rate, whereas IFS2 was down-regulated and highly correlated with isoflavone accumulation under both water deficit and well-watered conditions, suggesting IFS2 as a main contributor to isoflavone diminution under drought.	Isoflavones	247-257	2-hydroxyisoflavanone synthase	Glycine max	217-221	
16924535-1	2007	Soybean hairy roots, transformed with the soybean chalcone synthase (CHS6) or isoflavone synthase (IFS2) genes, with dramatically decreased capacity to synthesize isoflavones were produced to determine what effects these changes would have on susceptibility to a fungal pathogen.	Isoflavones	163-174	2-hydroxyisoflavanone synthase	Glycine max	99-103