PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20850430-8 2010 Our data suggest that the novel isoflavone derivatives inhibit osteoclastogenesis from bone marrow stromal cells and macrophage cells via attenuation of RANKL-induced p38, JNK and NF-kappaB activation. Isoflavones 32-42 mitogen-activated protein kinase 1 Homo sapiens 167-170 18955325-9 2010 We also investigated the effect of isoflavones on ERK and Akt pathways. Isoflavones 35-46 mitogen-activated protein kinase 1 Homo sapiens 50-53 19679176-7 2009 RESULTS: Our in vitro studies showed that UVB-induced HaCaT cell death and the phosphorylation of p38, JNK, and ERK1/2 decreased in the presence of isoflavone extract. Isoflavones 148-158 mitogen-activated protein kinase 1 Homo sapiens 98-101 17404070-10 2007 The COX-2 stimulatory effect of soy-isoflavones appeared to be modulated by ERK-1 and -2 and p38. Isoflavones 32-47 mitogen-activated protein kinase 1 Homo sapiens 93-96 12514295-6 2003 These data suggest an important interplay between the p38 pathway and G2 cell cycle checkpoint control and provide insights into possible mechanisms whereby this isoflavone may inhibit early events in mammary carcinogenesis. Isoflavones 162-172 mitogen-activated protein kinase 1 Homo sapiens 54-57