PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19591018-7	2009	The beneficial effect on metabolic diseases and weight reduction by isoflavone consumption can be partly explained by its affinity for the PPAR family.	Isoflavones	68-78	peroxisome proliferator activated receptor alpha	Homo sapiens	139-143	
22254019-0	2010	Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR.	Isoflavones	39-50	peroxisome proliferator activated receptor alpha	Homo sapiens	85-89	
22254019-4	2010	Isoflavones are potent dual PPARalpha/gamma agonists and exert anti-inflammatory activity, which may contribute to the prevention of metabolic syndrome, atherosclerosis and various other inflammatory diseases.	Isoflavones	0-11	peroxisome proliferator activated receptor alpha	Homo sapiens	28-37	
21461045-4	2010	These results suggest that isoflavones have other mechanisms of action, potentially those involving regulation of fatty acid metabolism via the nuclear receptors PPARalpha and PPARgamma.	Isoflavones	27-38	peroxisome proliferator activated receptor alpha	Homo sapiens	162-171	
21461045-5	2010	The goal of this paper was to examine the evidence for isoflavone/PPAR signaling and to identify diseases in which such signaling would have an important impact.	Isoflavones	55-65	peroxisome proliferator activated receptor alpha	Homo sapiens	66-70	
21461045-6	2010	It is therefore of note that investigators using a chemical structure approach to discover PPAR ligands identified isoflavones as the best structures in the library of compounds that they tested.	Isoflavones	115-126	peroxisome proliferator activated receptor alpha	Homo sapiens	91-95	
21461045-7	2010	Future studies will involve careful identification of the underlying mechanisms whereby isoflavones have their action via PPAR signaling.	Isoflavones	88-99	peroxisome proliferator activated receptor alpha	Homo sapiens	122-126	
26901838-0	2016	The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARalpha/gamma and JNK Pathways in Adipocyte and Macrophage Co-Cultures.	Isoflavones	12-22	peroxisome proliferator activated receptor alpha	Homo sapiens	85-94	
26901838-2	2016	Recently, the soy isoflavone daidzein was reported to act as a PPAR activator.	Isoflavones	18-28	peroxisome proliferator activated receptor alpha	Homo sapiens	63-67	
18555850-13	2008	Muscle PPARalpha and gamma expression was also increased with the isoflavone-depleted soy relative to either casein or soy protein containing the isoflavones.	Isoflavones	66-76	peroxisome proliferator activated receptor alpha	Homo sapiens	7-16	
18555850-13	2008	Muscle PPARalpha and gamma expression was also increased with the isoflavone-depleted soy relative to either casein or soy protein containing the isoflavones.	Isoflavones	146-157	peroxisome proliferator activated receptor alpha	Homo sapiens	7-16	
16549448-0	2006	Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARalpha, PPARgamma, and adipocyte differentiation in vitro.	Isoflavones	24-35	peroxisome proliferator activated receptor alpha	Homo sapiens	111-120