PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17404070-0 2007 Possible link between NO concentrations and COX-2 expression in systems treated with soy-isoflavones. Isoflavones 89-100 mitochondrially encoded cytochrome c oxidase II Homo sapiens 44-49 17404070-10 2007 The COX-2 stimulatory effect of soy-isoflavones appeared to be modulated by ERK-1 and -2 and p38. Isoflavones 32-47 mitochondrially encoded cytochrome c oxidase II Homo sapiens 4-9 16046614-5 2005 Both inhibitors decreased basal production of prostacyclin, but only COX-2 inhibition completely abolished the isoflavone-stimulated prostacyclin production. Isoflavones 111-121 mitochondrially encoded cytochrome c oxidase II Homo sapiens 69-74 22001128-13 2012 Soy isoflavones, linked to reduced cancer risk in Asian epidemiology, may suppress cox-2 induction by activating ERbeta. Isoflavones 4-15 mitochondrially encoded cytochrome c oxidase II Homo sapiens 83-88 16870006-10 2006 The results revealed that the hCOX-2 promoter transactivation suppressed by isoflavone could be dependent on AP-1/CREB binding. Isoflavones 76-86 mitochondrially encoded cytochrome c oxidase II Homo sapiens 30-36 23948065-3 2013 In this study, we found that the isoflavone, biochanin A, inhibited the expression of sUV-induced COX-2, which is a well-characterized sUV-induced enzyme, in both human HaCaT keratinocytes and JB6 P+ mouse skin epidermal cells. Isoflavones 33-43 mitochondrially encoded cytochrome c oxidase II Homo sapiens 98-103