PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23337939-10	2013	In conclusion, the isoflavones             daidzein and genistein showed anti-breast cancer activity, which was associated             with expression of the ERalpha and c-erbB-2 receptors.	Isoflavones	19-30	erb-b2 receptor tyrosine kinase 2	Homo sapiens	170-178	
28734033-2	2017	Epidemiological evidence linking lignans and isoflavones to Ki-67 and HER2 is limited.	Isoflavones	45-56	erb-b2 receptor tyrosine kinase 2	Homo sapiens	70-74	
22211813-5	2012	In HER2 negative cancer patients, isoflavone was inversely associated with breast cancer recurrence (HR: 0.23, 95% CI: 0.06-0.89; P for trend = 0.01).	Isoflavones	34-44	erb-b2 receptor tyrosine kinase 2	Homo sapiens	3-7	
22211813-7	2012	In conclusion, overall soy food intake might not affect the risk of cancer recurrence, but high intake of soy isoflavones increased the risk of cancer recurrence in HER2-positive breast cancer patients.	Isoflavones	110-121	erb-b2 receptor tyrosine kinase 2	Homo sapiens	165-169	
17295235-4	2007	Soy isoflavone genistein has been shown to have anti-cancer activities and suppress expression of HER2 and ERalpha.	Isoflavones	4-14	erb-b2 receptor tyrosine kinase 2	Homo sapiens	98-102	
12368416-10	2002	Hence, in the MMTV-neu mouse, soy isoflavones delayed mammary tumorigenesis.	Isoflavones	34-45	erb-b2 receptor tyrosine kinase 2	Homo sapiens	19-22	
12239620-0	2002	Soy isoflavone genistein modulates cell cycle progression and induces apoptosis in HER-2/neu oncogene expressing human breast epithelial cells.	Isoflavones	0-14	erb-b2 receptor tyrosine kinase 2	Homo sapiens	83-92	
11435074-0	2001	Overexpression of HER-2/neu enhances the sensitivity of human bladder cancer cells to urinary isoflavones.	Isoflavones	94-105	erb-b2 receptor tyrosine kinase 2	Homo sapiens	18-27	
11435074-3	2001	This study aimed to examine the potential of HER-2/neu as a biological target for soy isoflavones.	Isoflavones	86-97	erb-b2 receptor tyrosine kinase 2	Homo sapiens	45-54	
11435074-4	2001	The sensitivity of the bladder cancer cell lines (n=7) to the isoflavones was inversely related to the amount of HER-2/neu expressed.	Isoflavones	62-73	erb-b2 receptor tyrosine kinase 2	Homo sapiens	113-122	
11435074-5	2001	By using HER-2/neu transfection experiments, all three stable transfectants showed a significant growth inhibition by the isoflavone mixture at concentrations attainable in normal adult urine.	Isoflavones	122-132	erb-b2 receptor tyrosine kinase 2	Homo sapiens	9-14	
11435074-5	2001	By using HER-2/neu transfection experiments, all three stable transfectants showed a significant growth inhibition by the isoflavone mixture at concentrations attainable in normal adult urine.	Isoflavones	122-132	erb-b2 receptor tyrosine kinase 2	Homo sapiens	15-18	
11435074-7	2001	The results of this study suggest that HER-2/neu may be a practical biochemical target for urinary isoflavones in vivo.	Isoflavones	99-110	erb-b2 receptor tyrosine kinase 2	Homo sapiens	39-48