PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1968027-2	1990	The following results were obtained: 1) HDC activity in the gastric mucosa of rats treated with cimetidine (100 mg/kg twice daily) tended to increase in the intact region, and it was significantly increased in the ulcer region.	Cimetidine	96-106	histidine decarboxylase	Rattus norvegicus	40-43	
1968027-3	1990	2) Increased HDC activity due to cimetidine treatment was observed at the 10th day after interruption of cimetidine administration.	Cimetidine	33-43	histidine decarboxylase	Rattus norvegicus	13-16	
1968027-3	1990	2) Increased HDC activity due to cimetidine treatment was observed at the 10th day after interruption of cimetidine administration.	Cimetidine	105-115	histidine decarboxylase	Rattus norvegicus	13-16	
1968027-5	1990	The results suggest that the increased HDC activity in the gastric mucosa might participate in the relapse and recurrence of gastric ulcer after discontinuation of cimetidine administration.	Cimetidine	164-174	histidine decarboxylase	Rattus norvegicus	39-42	
2487969-2	1989	HDC activity was dose dependently activated by not only tetragastrin but also cimetidine and omeprazole treatment.	Cimetidine	78-88	histidine decarboxylase	Rattus norvegicus	0-3	
2487969-6	1989	Cimetidine and omeprazole induced the secretion of endogenous gastrin, leading to the activation of HDC.	Cimetidine	0-10	histidine decarboxylase	Rattus norvegicus	100-103	
6860344-4	1983	Administration of cimetidine increases histidine decarboxylase activity, decreases histamine level in gastric mucosa and inhibits gastric acid secretion.	Cimetidine	18-28	histidine decarboxylase	Rattus norvegicus	39-62