PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35178160-7 2022 This study firstly verified the PAOX upregulation in human degenerated disc samples and applied an IL-1beta-induced nucleus pulposus (NP) cell degeneration model to demonstrate that spermidine supplementation balanced polyamine metabolism and delayed NP cell senescence. Spermidine 182-192 interleukin 1 alpha Homo sapiens 99-107