PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22798207-0 2012 TRAIL resistance in human neuroblastoma SK-N-AS cells is dependent on protein kinase C and involves inhibition of caspase-3 proteolytic processing. sk-n 40-44 TNF superfamily member 10 Homo sapiens 0-5 30166400-6 2018 We also show that SBI-0206965 sensitizes SK-N-AS cells to TRAIL treatment, but not to mTOR inhibitors (INK128, Torin1) or topoisomerase inhibitors (doxorubicin, topotecan). sk-n 41-45 TNF superfamily member 10 Homo sapiens 58-63 22798207-4 2012 We have previously shown that the naturally occurring compound curcumin can sensitize SK-N-AS cells to TRAIL. sk-n 86-90 TNF superfamily member 10 Homo sapiens 103-108 12807432-1 2003 The SK-N-MC neuroblastoma cell line, which expresses surface tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors TRAIL-R2 and TRAIL-R4, was used as a model system to examine the effect of TRAIL on key intracellular pathways involved in the control of neuronal cell survival and apoptosis. sk-n 4-8 TNF superfamily member 10 Homo sapiens 119-124 21229292-9 2011 Furthermore, exposure of SK-N-AS cells to H(2)O(2) could mimic the TRAIL-sensitizing effect of other agents. sk-n 25-29 TNF superfamily member 10 Homo sapiens 67-72 21229292-10 2011 In conclusion, our results suggest that sensitization of neuroblastoma SK-N-AS cells to TRAIL-induced apoptosis is correlated with induction of reactive oxygen species (ROS) rather than inhibition of NF-kappaB. sk-n 71-75 TNF superfamily member 10 Homo sapiens 88-93 21229292-3 2011 The objective of this study was to investigate involvement of the transcription factor NF-kappaB in the resistance of human neuroblastoma SK-N-AS cells to TRAIL-induced apoptosis. sk-n 138-142 TNF superfamily member 10 Homo sapiens 155-160 12807432-1 2003 The SK-N-MC neuroblastoma cell line, which expresses surface tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors TRAIL-R2 and TRAIL-R4, was used as a model system to examine the effect of TRAIL on key intracellular pathways involved in the control of neuronal cell survival and apoptosis. sk-n 4-8 TNF superfamily member 10 Homo sapiens 136-141