PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9316423-1	1997	The goal of the current study was to examine whether polyamines are involved in the regulation of transcription and posttranscription of the protooncogenes c-myc and c-jun in intestinal epithelial cells.	Polyamines	53-63	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	156-161	
9316423-8	1997	Furthermore, direct administration of spermidine to isolated nuclei from polyamine-deficient (caused by DFMO) cells resulted in a 2- to 2.5-fold increase in c-myc and c-jun transcription.	Polyamines	73-82	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	157-162	
9316423-10	1997	These results indicate that 1) polyamines are required for the transcription of the protooncogenes c-myc and c-jun in IEC-6 cells and 2) depletion of intracellular polyamines has no effect on posttranscriptional regulation of c-myc and c-jun mRNAs.	Polyamines	31-41	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	99-104	
8572176-0	1995	Gastrin stimulates expression of protooncogene c-myc through a process involving polyamines in IEC-6 cells.	Polyamines	81-91	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	47-52	
8572176-9	1995	These results show that 1) gastrin stimulates both polyamine biosynthesis and the expression of the c-myc protooncogene, and 2) depletion of intracellular polyamines by DFMO significantly prevented the increased expression of c-myc by gastrin.	Polyamines	51-60	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	226-231	
8572176-9	1995	These results show that 1) gastrin stimulates both polyamine biosynthesis and the expression of the c-myc protooncogene, and 2) depletion of intracellular polyamines by DFMO significantly prevented the increased expression of c-myc by gastrin.	Polyamines	155-165	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	100-105	
8572176-9	1995	These results show that 1) gastrin stimulates both polyamine biosynthesis and the expression of the c-myc protooncogene, and 2) depletion of intracellular polyamines by DFMO significantly prevented the increased expression of c-myc by gastrin.	Polyamines	155-165	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	226-231	
8048943-2	1994	Elevation of cellular polyamine content triggered the transcription of c-myc and c-fos.	Polyamines	22-31	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	71-76	
8203532-1	1994	The current study determines the hypothesis that expression of protooncogenes c-fos and c-myc is involved in the mechanism of polyamine-stimulated healing in gastric mucosal stress ulcers.	Polyamines	126-135	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	88-93	
8368314-2	1993	This study tests the hypothesis that the protooncogenes c-fos, c-myc, c-jun, and junB are involved in the mechanism by which polyamines modulate mucosal growth.	Polyamines	125-135	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	63-68	
19812253-3	2009	Here, we show that in rat intestinal epithelial cells (IECs), polyamines enhanced HuR association with the 3"-untranslated region of the c-Myc mRNA by increasing HuR phosphorylation by Chk2, in turn promoting c-Myc translation.	Polyamines	62-72	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	137-142	
19812253-3	2009	Here, we show that in rat intestinal epithelial cells (IECs), polyamines enhanced HuR association with the 3"-untranslated region of the c-Myc mRNA by increasing HuR phosphorylation by Chk2, in turn promoting c-Myc translation.	Polyamines	62-72	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	209-214