PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11223914-3	2001	We have previously reported that amyloid beta-peptide (A beta), the main constituent of senile plaques in Alzheimer"s disease (AD) brain, is toxic to neurons through a free radical-dependent oxidative stress mechanism and that A beta(1--42), the principal form of A beta in AD brain, causes an increase in polyamine metabolism manifested by up-regulated polyamine uptake and increased ornithine decarboxylase (ODC) activity.	Polyamines	306-315	AA1	Homo sapiens	227-239	
11223914-3	2001	We have previously reported that amyloid beta-peptide (A beta), the main constituent of senile plaques in Alzheimer"s disease (AD) brain, is toxic to neurons through a free radical-dependent oxidative stress mechanism and that A beta(1--42), the principal form of A beta in AD brain, causes an increase in polyamine metabolism manifested by up-regulated polyamine uptake and increased ornithine decarboxylase (ODC) activity.	Polyamines	354-363	AA1	Homo sapiens	227-239