PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8759613-1	1996	Polyamine transport is strongly induced by insulin and estradiol (E2) in ZR-75-1 human breast cancer cells.	Polyamines	0-9	insulin	Homo sapiens	43-50	
20405312-5	2010	Polyamines have an insulin-like action.	Polyamines	0-10	insulin	Homo sapiens	19-26	
19568879-1	2008	OBJECTIVES: Polyamines have long been known to have an insulin-like action, but their antiglycating effect has only recently attracted the attention of researchers.	Polyamines	12-22	insulin	Homo sapiens	55-62	
17709892-5	2007	Unexpected observations were the pervasive effects of insulin on genes involved in interacting pathways for polyamine and S-adenoslymethionine metabolism and genes involved in muscle development.	Polyamines	108-117	insulin	Homo sapiens	54-61	
8759613-6	1996	Interferon-gamma inhibited IL-4- and IL-13-dependent spermidine uptake to a much greater extent than basal or insulin-induced transport of the polyamine.	Polyamines	143-152	insulin	Homo sapiens	110-117	
1637336-12	1992	Overall, the data provide further evidence against a role for polyamines in the rapid stimulation of PDH by insulin, but suggest that polyamines may be important in mediating longer-term changes in the activity of the complex.	Polyamines	62-72	insulin	Homo sapiens	108-115	
2697686-0	1989	Decreased cell replication and polyamine content in insulin-producing cells after exposure to human interleukin 1 beta.	Polyamines	31-40	insulin	Homo sapiens	52-59	
1583348-6	1992	The results suggest that enhanced polyamine biosynthesis and catabolism, particularly N1-acetylation, occur in cirrhotic patients, probably due to hepatic regeneration and/or increased levels of insulin and glucagon.	Polyamines	34-43	insulin	Homo sapiens	195-202	
2083920-8	1990	When insulin and glucagon infusion therapy was performed in patients with liver cirrhosis without ascites, urinary polyamine excretion was significantly elevated after three days.	Polyamines	115-124	insulin	Homo sapiens	5-12	
35448531-4	2022	Recently, it has been demonstrated that activity of the polyamines-hypusine circuit in insulin-producing islet beta cells contributes to diabetes pathogenesis under conditions of inflammation.	Polyamines	56-66	insulin	Homo sapiens	87-94	
34902085-3	2021	Polyamines, organic compounds synthesized by cardiomyocytes, have an insulin-like activity and effect on glucose metabolism, making them metabolites of interest in the DM heart.	Polyamines	0-10	insulin	Homo sapiens	69-76	
34902085-9	2021	This review discusses the regulation of polyamine synthesis and metabolism, and its impact on cardiac metabolism and circulating levels of glucose, insulin, and ketone bodies.	Polyamines	40-49	insulin	Homo sapiens	148-155	
2557012-4	1989	263, 2377-2383], we examined the effects of a variety of basic polycations/proteins and polyamines on insulin receptor kinase activity.	Polyamines	88-98	insulin	Homo sapiens	102-109	
6151406-3	1984	The concentration of polyamines found in islets were high enough for them to act as substrates for the Ca2+-dependent islet transglutaminase during insulin release.	Polyamines	21-31	insulin	Homo sapiens	148-155	
3142887-8	1988	The recruitment of the polyamine-depleted, serum-deprived cells into the cell division cycle does not require PDGF and can be induced by addition of EGF and insulin plus putrescine.	Polyamines	23-32	insulin	Homo sapiens	157-164	
3901680-4	1985	Among these hormones, only insulin, dexamethasone and EGF induced ODC activity and polyamine biosynthesis, especially that of putrescine, in both adult and fetal hepatocytes.	Polyamines	83-92	insulin	Homo sapiens	27-34	
31889346-0	2020	Insulin-Delivery from Glucose-Responsive Self-Assembled Polyamine Nanoparticles: Smart "Sense-and-Treat" Nanocarriers Made Easy.	Polyamines	56-65	insulin	Homo sapiens	0-7	
833144-0	1977	Insulin-like effects of polyamines in fat cells.	Polyamines	24-34	insulin	Homo sapiens	0-7	
833144-5	1977	The insulin-like effects elicited by polyamines in fat cells (e.g. enhancement of glucose transport and inhibition of cAMP-mediated lipolysis) were dependent on H2O2 production.	Polyamines	37-47	insulin	Homo sapiens	4-11	
833144-9	1977	These findings indicate that the polyamines do not themselves mimic the actions of insulin but that the insulin-like effects result from the formation of H2O2 which has been shown to stimulate glucose transport.	Polyamines	33-43	insulin	Homo sapiens	104-111