PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10582125-2	1999	In the present study developmental patterns of renal polyamine-oxidizing enzymes polyamine oxidase (PAO) and diamine oxidase (DAO) in male and female ICR mice were demonstrated.	Polyamines	53-62	polyamine oxidase (exo-N4-amino)	Mus musculus	81-98	
19199575-3	2009	The effects of pH on the kinetic parameters of mouse PAO have been determined to provide insight into the protonation state of the polyamine required for catalysis and the roles of ionizable residues in the active site in amine oxidation.	Polyamines	131-140	polyamine oxidase (exo-N4-amino)	Mus musculus	53-56	
12660232-11	2003	Thus, this is the classical polyamine oxidase (EC 1.5.3.11) that is defined as the enzyme that oxidizes these N1-acetylated polyamines on the exo-side of their N4-amino groups.	Polyamines	124-134	polyamine oxidase (exo-N4-amino)	Mus musculus	28-45	
24717514-7	2014	Polyamine flux including synthesis, catabolism and excretion, is controlled by the rate-limiting enzymes ornithine decarboxylase (ODC) and spermidine-spermine N(1)-acetyltransferase (SSAT; encoded by Sat1) and by polyamine oxidase (PAO), and has a major role in energy metabolism.	Polyamines	0-9	polyamine oxidase (exo-N4-amino)	Mus musculus	213-230	
24717514-7	2014	Polyamine flux including synthesis, catabolism and excretion, is controlled by the rate-limiting enzymes ornithine decarboxylase (ODC) and spermidine-spermine N(1)-acetyltransferase (SSAT; encoded by Sat1) and by polyamine oxidase (PAO), and has a major role in energy metabolism.	Polyamines	0-9	polyamine oxidase (exo-N4-amino)	Mus musculus	232-235	
10582125-2	1999	In the present study developmental patterns of renal polyamine-oxidizing enzymes polyamine oxidase (PAO) and diamine oxidase (DAO) in male and female ICR mice were demonstrated.	Polyamines	53-62	polyamine oxidase (exo-N4-amino)	Mus musculus	100-103	
10582125-14	1999	It could be suggested that our data indicate the different contribution of renal PAO and DAO in androgen regulation of polyamine levels, depending on sex and the stage of the postnatal development.	Polyamines	119-128	polyamine oxidase (exo-N4-amino)	Mus musculus	81-84	
9879934-9	1998	The correlation between the cytotoxic results and the intracellular polyamine determination shows that the increase in spermine content along with the inhibition of retroconverting PAO enzyme increases the toxic effect of tested compounds (including spermine), suggesting that spermine toxicity is more important in the absence of intracellular oxidation processes.	Polyamines	68-77	polyamine oxidase (exo-N4-amino)	Mus musculus	181-184	
29477597-1	2018	Inhibitors for polyamine oxidizing enzymes, spermine oxidase (SMOX) and N1-acetylpolyamine oxidase (PAOX), were designed and evaluated for their effectiveness in a photochemically induced thrombosis (PIT) mouse model.	Polyamines	15-24	polyamine oxidase (exo-N4-amino)	Mus musculus	100-104	
2241104-0	1990	Antitumor activity of a novel synthetic polyamine analogue, N,N"-bis-[3-(ethylamino)-propyl]-1-7-heptane diamine: potentiation by polyamine oxidase inhibitors.	Polyamines	40-49	polyamine oxidase (exo-N4-amino)	Mus musculus	130-147	
1510731-3	1992	A second enzyme of polyamine back-conversion, murine polyamine oxidase (PAO), was found to be competitively inhibited by pentamidine, with a Ki of 7.6 microM when N-acetylspermine was the substrate.	Polyamines	19-28	polyamine oxidase (exo-N4-amino)	Mus musculus	53-70	
1510731-3	1992	A second enzyme of polyamine back-conversion, murine polyamine oxidase (PAO), was found to be competitively inhibited by pentamidine, with a Ki of 7.6 microM when N-acetylspermine was the substrate.	Polyamines	19-28	polyamine oxidase (exo-N4-amino)	Mus musculus	72-75	
30829081-5	2019	Methoctramine is a very promising tool in the design of drugs targeting the polyamine catabolism pathway, both to understand the physio-pathological role of PAOX vs SMOX and for pharmacological applications, being the polyamine pathway involved in various pathologies.	Polyamines	76-85	polyamine oxidase (exo-N4-amino)	Mus musculus	157-161	
30829081-5	2019	Methoctramine is a very promising tool in the design of drugs targeting the polyamine catabolism pathway, both to understand the physio-pathological role of PAOX vs SMOX and for pharmacological applications, being the polyamine pathway involved in various pathologies.	Polyamines	218-227	polyamine oxidase (exo-N4-amino)	Mus musculus	157-161