PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31548311-3 2019 Yeast strains deficient in polyamine biosynthesis (spe1 , lacking ornithine decarboxylase, and spe2 , lacking S-adenosylmethionine decarboxylase) require externally supplied polyamines, but supplementation with as little as 10-8 M spermidine restores their growth. Polyamines 27-36 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 95-99 7961484-0 1994 SPE1 and SPE2: two essential genes in the biosynthesis of polyamines that modulate +1 ribosomal frameshifting in Saccharomyces cerevisiae. Polyamines 58-68 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 9-13 8506320-0 1993 Oxygen toxicity in a polyamine-depleted spe2 delta mutant of Saccharomyces cerevisiae. Polyamines 21-30 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 40-44 8506320-1 1993 When a mutant of Saccharomyces cerevisiae (spe2 delta) that cannot make spermidine or spermine was incubated in a polyamine-deficient medium in oxygen, there was a rapid cessation of cell growth and associated cell death. Polyamines 114-123 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 43-47 31548311-7 2019 In contrast, a spe2 alr1 double mutant cultured in SDC medium exhibited little increase in Mg2+ content and displayed severe growth defects compared with single mutants, alr1 and spe2 , under polyamine-deficient conditions. Polyamines 195-204 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 15-25 31548311-7 2019 In contrast, a spe2 alr1 double mutant cultured in SDC medium exhibited little increase in Mg2+ content and displayed severe growth defects compared with single mutants, alr1 and spe2 , under polyamine-deficient conditions. Polyamines 195-204 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 15-19 12042867-2 2002 We expressed a yeast S-adenosylmethionine decarboxylase gene (ySAMdc; Spe2) fused with a ripening-inducible E8 promoter to specifically increase levels of the polyamines spermidine and spermine in tomato fruit during ripening. Polyamines 159-169 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 70-74 9442051-2 1998 Disruption of the SPE2 gene encoding S-adenosylmethionine decarboxylase, which catalyzes an essential step in polyamine biosynthesis, upregulated the initial velocity of spermidine uptake in wild-type cells as well as in the polyamine transport-deficient pcp1 mutants. Polyamines 110-119 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 18-22 9442051-2 1998 Disruption of the SPE2 gene encoding S-adenosylmethionine decarboxylase, which catalyzes an essential step in polyamine biosynthesis, upregulated the initial velocity of spermidine uptake in wild-type cells as well as in the polyamine transport-deficient pcp1 mutants. Polyamines 225-234 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 18-22 9442051-5 1998 The stability of polyamine carrier activity was increased 2-fold in polyamine-depleted spe2 deletion mutants, indicating that endogenous polyamines also contribute to the down-regulation of spermidine transport. Polyamines 17-26 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 87-91 9442051-5 1998 The stability of polyamine carrier activity was increased 2-fold in polyamine-depleted spe2 deletion mutants, indicating that endogenous polyamines also contribute to the down-regulation of spermidine transport. Polyamines 68-77 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 87-91 9442051-5 1998 The stability of polyamine carrier activity was increased 2-fold in polyamine-depleted spe2 deletion mutants, indicating that endogenous polyamines also contribute to the down-regulation of spermidine transport. Polyamines 137-147 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 87-91 31548311-3 2019 Yeast strains deficient in polyamine biosynthesis (spe1 , lacking ornithine decarboxylase, and spe2 , lacking S-adenosylmethionine decarboxylase) require externally supplied polyamines, but supplementation with as little as 10-8 M spermidine restores their growth. Polyamines 174-184 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 95-99 31548311-4 2019 Here, we report that culturing a spe1 mutant or a spe2 mutant in standard polyamine-free minimal medium (SDC) leads to marked increases cellular Mg2+ content. Polyamines 76-85 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 51-55 21742865-5 2011 A yeast-two-hybrid screen showed that HtpB interacted with S-adenosylmethionine decarboxylase (SAMDC), an essential yeast enzyme (encoded by SPE2) that is required for polyamine biosynthesis. Polyamines 168-177 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 141-145 21742865-6 2011 Increasing the copy number of SPE2 induced pseudohyphal growth in S. cerevisiae; thus, we speculated that (i) HtpB induces pseudohyphal growth by activating polyamine synthesis and (ii) L. pneumophila may require exogenous polyamines for growth. Polyamines 157-166 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 30-34 21742865-6 2011 Increasing the copy number of SPE2 induced pseudohyphal growth in S. cerevisiae; thus, we speculated that (i) HtpB induces pseudohyphal growth by activating polyamine synthesis and (ii) L. pneumophila may require exogenous polyamines for growth. Polyamines 223-233 adenosylmethionine decarboxylase SPE2 Saccharomyces cerevisiae S288C 30-34