PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7945802-7 1994 These data show that polyamine depletion by DFMO can suppress the expression of matrilysin, a gene product thought to be involved in tumor invasion. Polyamines 21-30 matrix metallopeptidase 7 Homo sapiens 80-90 16170669-0 2005 Inhibitors of polyamine biosynthesis decrease the expression of the metalloproteases meprin alpha and MMP-7 in hormone-independent human breast cancer cells. Polyamines 14-23 matrix metallopeptidase 7 Homo sapiens 102-107 16170669-6 2005 Treatment of cells with a second inhibitor of polyamine biosynthesis, the S-adenosylmethionine decarboxylase (SAMDC) inhibitor SAM486A, also resulted in a dosage dependent decrease in meprin alpha and MMP-7 mRNA. Polyamines 46-55 matrix metallopeptidase 7 Homo sapiens 201-206 7945802-0 1994 Polyamine-dependent expression of the matrix metalloproteinase matrilysin in a human colon cancer-derived cell line. Polyamines 0-9 matrix metallopeptidase 7 Homo sapiens 63-73 7945802-8 1994 The decrease in extracellular matrilysin protein caused by DFMO treatment appears to be due to a posttranscriptional mechanism, although transcription of this gene also seems to be affected by polyamines in SW1116 cells. Polyamines 193-203 matrix metallopeptidase 7 Homo sapiens 30-40