PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9202318-1 1997 S-Adenosyl-L-methionine decarboxylase (SAMdc) and L-ornithine decarboxylase (ODC) are major enzymes regulating polyamine synthesis. Polyamines 111-120 adenosylmethionine decarboxylase 1 Rattus norvegicus 0-37 12239599-6 2002 In the residual small intestine, the expression of polyamine synthesis enzymes, ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC) mRNAs were increased on POD 1. Polyamines 51-60 adenosylmethionine decarboxylase 1 Rattus norvegicus 150-155 10620005-8 2000 Polyamines were subsequently accumulated in both skeletal muscle fibres, with a rise in putrescine concentration after 2 h, and a fall corresponding to conversion of putrescine to spermidine and spermine by SAMDC. Polyamines 0-10 adenosylmethionine decarboxylase 1 Rattus norvegicus 207-212 9202318-1 1997 S-Adenosyl-L-methionine decarboxylase (SAMdc) and L-ornithine decarboxylase (ODC) are major enzymes regulating polyamine synthesis. Polyamines 111-120 adenosylmethionine decarboxylase 1 Rattus norvegicus 39-44 9202318-11 1997 Decreased SAMdc activity impairs the conversion of putrescine to polyamines and may contribute to delayed pathological changes in the brain after traumatic injury. Polyamines 65-75 adenosylmethionine decarboxylase 1 Rattus norvegicus 10-15 9243121-0 1997 Importance of intracellular S-adenosylmethionine decarboxylase activity for the regulation of camostate-induced pancreatic polyamine metabolism and growth: in vivo effect of two novel S-adenosylmethionine decarboxylase inhibitors. Polyamines 123-132 adenosylmethionine decarboxylase 1 Rattus norvegicus 28-62 2114097-0 1990 Specific regulation by endogenous polyamines of translational initiation of S-adenosylmethionine decarboxylase mRNA in Swiss 3T3 fibroblasts. Polyamines 34-44 adenosylmethionine decarboxylase 1 Rattus norvegicus 76-110 1415709-1 1992 Two key enzymes in polyamine biosynthesis are ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC). Polyamines 19-28 adenosylmethionine decarboxylase 1 Rattus norvegicus 80-114 1415709-1 1992 Two key enzymes in polyamine biosynthesis are ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC). Polyamines 19-28 adenosylmethionine decarboxylase 1 Rattus norvegicus 116-121 2114097-1 1990 S-Adenosylmethionine decarboxylase (AdoMetDC) activity was elevated 18.8-fold in Swiss 3T3 fibroblasts which were depleted of cellular polyamines by using the inhibitor difluoromethylornithine (DFMO). Polyamines 135-145 adenosylmethionine decarboxylase 1 Rattus norvegicus 0-34 2114097-1 1990 S-Adenosylmethionine decarboxylase (AdoMetDC) activity was elevated 18.8-fold in Swiss 3T3 fibroblasts which were depleted of cellular polyamines by using the inhibitor difluoromethylornithine (DFMO). Polyamines 135-145 adenosylmethionine decarboxylase 1 Rattus norvegicus 36-44 2114097-3 1990 These data suggested that the translation of AdoMetDC mRNA must be increased in the polyamine-depleted cells to account fully for the elevation in activity. Polyamines 84-93 adenosylmethionine decarboxylase 1 Rattus norvegicus 45-53 2114097-4 1990 The cellular distribution of AdoMetDC mRNA was examined in the polyamine-depleted cells, and it was found almost exclusively associated with large polysomes. Polyamines 63-72 adenosylmethionine decarboxylase 1 Rattus norvegicus 29-37 2114097-7 1990 The effect of polyamine depletion on AdoMetDC translation was specific, since there was no change in the distribution in polysomes of either actin mRNA or the translationally controlled mRNA encoding ribosomal protein S16 in the DFMO-inhibited cells. Polyamines 14-23 adenosylmethionine decarboxylase 1 Rattus norvegicus 37-45 2114097-8 1990 Thus the translational efficiency of AdoMetDC mRNA in vivo is regulated either directly or indirectly by the concentration of intracellular polyamines through a mechanism involving translational initiation, which results in a change in the number of ribosomes associated with this mRNA. Polyamines 140-150 adenosylmethionine decarboxylase 1 Rattus norvegicus 37-45 3493704-2 1987 The effect of peptides on ODC and S-adenosylmethionine (SAMDC) activities (key enzymes in polyamine biosynthesis) in isolated enterocytes is unknown. Polyamines 90-99 adenosylmethionine decarboxylase 1 Rattus norvegicus 56-61 2796592-11 1989 The results indicate that BSP could cause changes in hepatic polyamine content due to the induction of ODC and SAMDC. Polyamines 61-70 adenosylmethionine decarboxylase 1 Rattus norvegicus 111-116 2930485-1 1989 A bisbenzyl polyamine analogue, MDL 27695, rapidly repressed ornithine decarboxylase (ODC) and S-adenosyl-L-methionine decarboxylase (AdoMet DC) activity and depleted polyamines in rat hepatoma (HTC) cells. Polyamines 167-177 adenosylmethionine decarboxylase 1 Rattus norvegicus 134-143 2930485-2 1989 The suppression of ODC and AdoMet DC activity was temporally related to metabolism of MDL 27695 by intracellular polyamine oxidase to a free-amine analogue, MDL 26752, which, when added directly to HTC cells, suppressed ODC activity and polyamine biosynthesis more rapidly and to a greater extent than did the bisbenzyl analogue. Polyamines 113-122 adenosylmethionine decarboxylase 1 Rattus norvegicus 27-36 6619973-1 1983 The purpose of this study was to investigate the dietary regulation of the two key enzymes in polyamine biosynthesis, ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC) in rat tissues. Polyamines 94-103 adenosylmethionine decarboxylase 1 Rattus norvegicus 152-186 6420041-3 1984 This suggests that inhibition of polyamine biosynthetic enzymes, ornithine decarboxylase (ODC) and S-adenosyl-methionine decarboxylase (SAMDC) may retard the growth of prostatic cancer. Polyamines 33-42 adenosylmethionine decarboxylase 1 Rattus norvegicus 99-134 6420041-3 1984 This suggests that inhibition of polyamine biosynthetic enzymes, ornithine decarboxylase (ODC) and S-adenosyl-methionine decarboxylase (SAMDC) may retard the growth of prostatic cancer. Polyamines 33-42 adenosylmethionine decarboxylase 1 Rattus norvegicus 136-141 6638190-1 1983 Transient increases in the activities of ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAM-DC), key enzymes in polyamine biosynthesis, may be critical to initiation of cell growth. Polyamines 135-144 adenosylmethionine decarboxylase 1 Rattus norvegicus 75-109 6638190-1 1983 Transient increases in the activities of ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAM-DC), key enzymes in polyamine biosynthesis, may be critical to initiation of cell growth. Polyamines 135-144 adenosylmethionine decarboxylase 1 Rattus norvegicus 111-117 6619973-1 1983 The purpose of this study was to investigate the dietary regulation of the two key enzymes in polyamine biosynthesis, ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC) in rat tissues. Polyamines 94-103 adenosylmethionine decarboxylase 1 Rattus norvegicus 188-193