PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26604686-2 2015 The drug suppresses the synthesis of proinflammatory enzymes, such as cyclo-oxygenases-1 and -2 (COX-1 and 2), downregulates the production of prostaglandins (PGs) and tromboxanes, and inhibits polyamines production by blocking ornithine decarboxylase induction involved in nonmelanoma skin carcinogenesis. Polyamines 194-204 mitochondrially encoded cytochrome c oxidase I Homo sapiens 97-108