PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24965651-8	2014	In mice infected with NDM-1-expressing Klebsiella pneumoniae, AMA efficiently restored meropenem activity, demonstrating that a combination of AMA and a carbapenem antibiotic has therapeutic potential to address the clinical challenge of MBL-positive carbapenem-resistant Gram-negative pathogens.	Carbapenems	153-163	mannose-binding lectin (protein C) 2	Mus musculus	238-241	
34903857-5	2022	Crystallographic studies revealed a binding mode of the InCs to MBLs that, in some regards, mimics that predicted for intact carbapenems, including with respect to maintenance of the Zn(II)-bound hydroxyl, and in other regards mimics binding observed in MBL-carbapenem product complexes.	Carbapenems	258-268	mannose-binding lectin (protein C) 2	Mus musculus	254-257	
33179050-1	2021	BACKGROUND: Using murine models of infection, we previously reported the potent in vivo activity of carbapenems against MBL-producing Enterobacterales despite the observed resistance in vitro.	Carbapenems	100-111	mannose-binding lectin (protein C) 2	Mus musculus	120-123	
32790873-3	2020	OBJECTIVES: To evaluate the activity of carbapenems alone or combined with DMSA against MBL-producing Escherichia coli in a severe murine peritonitis model.	Carbapenems	40-51	mannose-binding lectin (protein C) 2	Mus musculus	88-91	
32790873-7	2020	Bacterial counts in peritoneal fluid and spleen were assessed at 24 h. RESULTS: DMSA in combination with each carbapenem caused a significant decrease in the MICs for all MBL-producing strains, in a concentration-dependent manner, but did not provide benefit against non-MBL strains.	Carbapenems	110-120	mannose-binding lectin (protein C) 2	Mus musculus	171-174	
32790873-7	2020	Bacterial counts in peritoneal fluid and spleen were assessed at 24 h. RESULTS: DMSA in combination with each carbapenem caused a significant decrease in the MICs for all MBL-producing strains, in a concentration-dependent manner, but did not provide benefit against non-MBL strains.	Carbapenems	110-120	mannose-binding lectin (protein C) 2	Mus musculus	271-274	
32790873-10	2020	CONCLUSIONS: DMSA restores the activity of carbapenems against MBL-producing strains, and its combination with carbapenems appears to be a promising strategy for the treatment of NDM-producing E. coli infections.	Carbapenems	43-54	mannose-binding lectin (protein C) 2	Mus musculus	63-66	
24965651-8	2014	In mice infected with NDM-1-expressing Klebsiella pneumoniae, AMA efficiently restored meropenem activity, demonstrating that a combination of AMA and a carbapenem antibiotic has therapeutic potential to address the clinical challenge of MBL-positive carbapenem-resistant Gram-negative pathogens.	Carbapenems	251-261	mannose-binding lectin (protein C) 2	Mus musculus	238-241