PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26146906-12	2015	Conversely, methamphetamine-induced locomotor activity was attenuated in DKO mice, accompanied by reductions in dopamine and HVA content and impaired DARPP-32 activation.	Methamphetamine	12-27	protein phosphatase 1, regulatory inhibitor subunit 1B	Mus musculus	150-158	
22564758-2	2012	This study investigates the effects of naloxonazine, a specific mu-opioid receptor antagonist, on the locomotor behavioral response and phosphorylation pattern of dopamine and cAMP-regulated phosphoprotein of Mr32 (DARPP-32) in striatal dopaminergic transmissions induced by acute administration of METH to mice.	Methamphetamine	299-303	protein phosphatase 1, regulatory inhibitor subunit 1B	Mus musculus	163-213	
22564758-2	2012	This study investigates the effects of naloxonazine, a specific mu-opioid receptor antagonist, on the locomotor behavioral response and phosphorylation pattern of dopamine and cAMP-regulated phosphoprotein of Mr32 (DARPP-32) in striatal dopaminergic transmissions induced by acute administration of METH to mice.	Methamphetamine	299-303	protein phosphatase 1, regulatory inhibitor subunit 1B	Mus musculus	215-223	
22564758-7	2012	Results show that pretreatment with naloxonazine significantly attenuated the acute METH-induced increase in locomotor activity and phosphor-Thr75 DARPP-32 levels.	Methamphetamine	84-88	protein phosphatase 1, regulatory inhibitor subunit 1B	Mus musculus	147-155	
17010100-0	2006	Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARPP32 double-knockout mice.	Methamphetamine	61-76	protein phosphatase 1, regulatory inhibitor subunit 1B	Mus musculus	128-135	
17010100-4	2006	Analysis of the response to d-methamphetamine on locomotor activity showed that the hyperactivity experienced by PDE1B mutant mice was blocked in PDE1B-/- x DARPP32-/- double-KO mice, consistent with participation of PDE1B and DARPP32 in the same pathway.	Methamphetamine	28-45	protein phosphatase 1, regulatory inhibitor subunit 1B	Mus musculus	157-164	
17010100-4	2006	Analysis of the response to d-methamphetamine on locomotor activity showed that the hyperactivity experienced by PDE1B mutant mice was blocked in PDE1B-/- x DARPP32-/- double-KO mice, consistent with participation of PDE1B and DARPP32 in the same pathway.	Methamphetamine	28-45	protein phosphatase 1, regulatory inhibitor subunit 1B	Mus musculus	227-234