PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16338084-8 2006 Compared with controls, methamphetamine+Tat-treated animals showed extensive silver staining and loss of tyrosine hydroxylase immunoreactivity and protein levels in the ipsilateral striatum. Methamphetamine 24-39 tyrosine aminotransferase Homo sapiens 40-43 31269883-2 2019 HIV-associated proteins, such as the regulatory protein TAT, may contribute to brain reward dysfunction, inducing an altered sensitivity to methamphetamine reward and/or withdrawal in this population. Methamphetamine 140-155 tyrosine aminotransferase Homo sapiens 56-59 16338084-10 2006 Markers for oxidative stress were significantly increased in striatal synaptosomes from Tat+methamphetamine group compared with controls. Methamphetamine 92-107 tyrosine aminotransferase Homo sapiens 88-91 33815104-10 2021 In summary, the TRPM2 channel can regulate METH- and HIV-Tat-induced oxidative stress and BBB injury, giving the channel potential for developing drug interventions to reduce BBB injury and neuropsychiatric symptoms in HIV-infected METH abusers. Methamphetamine 232-236 tyrosine aminotransferase Homo sapiens 57-60 33815104-1 2021 Synergistic impairment of the blood-brain barrier (BBB) induced by methamphetamine (METH) and HIV-Tat protein increases the risk of HIV-associated neurocognitive disorders (HAND) in HIV-positive METH abusers. Methamphetamine 195-199 tyrosine aminotransferase Homo sapiens 98-101 12504868-3 2003 We hypothesize that abusive drugs, such as methamphetamine (METH), can directly influence specific molecular processes that can further contribute to toxic effects of Tat. Methamphetamine 43-58 tyrosine aminotransferase Homo sapiens 167-170 12504868-3 2003 We hypothesize that abusive drugs, such as methamphetamine (METH), can directly influence specific molecular processes that can further contribute to toxic effects of Tat. Methamphetamine 60-64 tyrosine aminotransferase Homo sapiens 167-170 32891668-0 2021 Both HIV and Tat expression decrease prepulse inhibition with further impairment by methamphetamine. Methamphetamine 84-99 tyrosine aminotransferase Homo sapiens 13-16