PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9563900-0 1998 Interleukin 6 differentially potentiates the antitumor effects of taxol and vinblastine in U266 human myeloma cells. Vinblastine 76-87 interleukin 6 Homo sapiens 0-13 9563900-6 1998 In the presence of IL-6, the DNA distribution pattern induced by Taxol or vinblastine was altered. Vinblastine 74-85 interleukin 6 Homo sapiens 19-23 9563900-11 1998 In the presence of IL-6, the number of cells containing microtubule asters increased for Taxol treatment, but not for vinblastine treatment. Vinblastine 118-129 interleukin 6 Homo sapiens 19-23 9563900-12 1998 These data indicate that IL-6 leads to differential modulation of the cytotoxicity of Taxol and vinblastine in U266 cells. Vinblastine 96-107 interleukin 6 Homo sapiens 25-29 9563900-13 1998 Whereas recruitment of cells in the S phase of the cell cycle represents a major mechanism by which IL-6 potentiates the cytotoxicity of vinblastine, augmentation of the cytotoxicity of Taxol involves additional mechanisms. Vinblastine 137-148 interleukin 6 Homo sapiens 100-104