PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32640500-4	2020	Transcriptome analysis of hPSCs derived hemogenic endothelial cells showed that ALA promoted endothelial-to-hematopoietic transition by up-regulating RUNX1, GFI1, GFI1B, MEIS2, and HIF1A and down-regulating SOX17, TGFB1, TGFB2, TGFB3, TGFBR1, and TGFBR2.	Thioctic Acid	80-83	transforming growth factor beta 1	Homo sapiens	214-219	
35401218-13	2022	Conclusion: Triple combination therapy of ALA, gliclazide and ramipril prevented DCM development by inhibiting TGF-beta1/Smad pathway.	Thioctic Acid	42-45	transforming growth factor beta 1	Homo sapiens	111-120	
31958458-7	2020	Lipoic acid also prevented the TGFbeta1 release and inhibited the radiation-induced EMT in breast cancer cells.	Thioctic Acid	0-11	transforming growth factor beta 1	Homo sapiens	31-39	
31958458-8	2020	The inhibition of TGFbeta signaling by lipoic acid is associated with the inhibition of radiation-induced activation and translocation of NF-kappaB.	Thioctic Acid	39-50	transforming growth factor beta 1	Homo sapiens	18-25	
31958458-9	2020	These results suggest that alpha-lipoic acid inhibits the radiation-induced TGFbeta signaling and nuclear translocation of NF-kappaB, thereby inhibiting the radiation-induced EMT and sensitizing the breast cancer cells to ionizing radiation.	Thioctic Acid	27-44	transforming growth factor beta 1	Homo sapiens	76-83	
24172699-11	2013	Alpha-lipoic acid significantly increased glutathione level and significantly decreased MDA, NO, TNF-alpha, Fas-L, MMP-2, troponin-I levels, and TGF-beta gene expression.	Thioctic Acid	0-17	transforming growth factor beta 1	Homo sapiens	145-153	
28349254-9	2018	Cell proliferation under HS conditions was improved by ALA supplementation as demonstrated in an epithelial wound healing assay and ALA was able to affect the HS-induced inflammatory response by decreasing the COX-2 and TGF-beta mRNA expression.	Thioctic Acid	132-135	transforming growth factor beta 1	Homo sapiens	220-228	
26463583-2	2016	Recent studies suggested the possibility of ALA as a potential anti-cancer agent, because it could activate adenosine monophosphate activated protein kinase (AMPK) and inhibit transforming growth factor-beta (TGFbeta) pathway.	Thioctic Acid	44-47	transforming growth factor beta 1	Homo sapiens	176-207	
26463583-2	2016	Recent studies suggested the possibility of ALA as a potential anti-cancer agent, because it could activate adenosine monophosphate activated protein kinase (AMPK) and inhibit transforming growth factor-beta (TGFbeta) pathway.	Thioctic Acid	44-47	transforming growth factor beta 1	Homo sapiens	209-216	
26463583-8	2016	ALA suppressed TGFbeta production and inhibited induction of p-Smad2 and twist by TGFbeta1 or TGFbeta2.	Thioctic Acid	0-3	transforming growth factor beta 1	Homo sapiens	15-22	
26463583-8	2016	ALA suppressed TGFbeta production and inhibited induction of p-Smad2 and twist by TGFbeta1 or TGFbeta2.	Thioctic Acid	0-3	transforming growth factor beta 1	Homo sapiens	82-90	
26463583-9	2016	These findings indicate that ALA reduces cancer cell migration and invasion through suppression of TGFbeta production and inhibition of TGFbeta signaling pathways in thyroid cancer cells.	Thioctic Acid	29-32	transforming growth factor beta 1	Homo sapiens	99-106	
26463583-9	2016	These findings indicate that ALA reduces cancer cell migration and invasion through suppression of TGFbeta production and inhibition of TGFbeta signaling pathways in thyroid cancer cells.	Thioctic Acid	29-32	transforming growth factor beta 1	Homo sapiens	136-143	
22065919-9	2011	TGF-beta1 levels were elevated in rapamycin group and rapamycin + ALA group.	Thioctic Acid	66-69	transforming growth factor beta 1	Homo sapiens	0-9