PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28070105-8 2017 Furthermore, alpha-LA restored the TCDD-produced reduction in the pituitary expression of the receptor for gonadotropin-releasing hormone (GnRH), an upstream regulator of LH synthesis. Thioctic Acid 13-21 gonadotropin releasing hormone 1 Rattus norvegicus 107-137 28070105-8 2017 Furthermore, alpha-LA restored the TCDD-produced reduction in the pituitary expression of the receptor for gonadotropin-releasing hormone (GnRH), an upstream regulator of LH synthesis. Thioctic Acid 13-21 gonadotropin releasing hormone 1 Rattus norvegicus 139-143 28070105-9 2017 These results suggest that alpha-LA rescues TCDD-produced attenuation during fetal steroidogenesis due not only to facilitation of energy production through the TCA cycle but also through suppression of AMPK activation, and the pituitary GnRH receptor may serve as a mediator of these effects. Thioctic Acid 27-35 gonadotropin releasing hormone 1 Rattus norvegicus 238-242